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HAMAP rule MF_00991

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General rule information [?]

Accession MF_00991
Dates 14-FEB-2014 (Created)
1-JUN-2023 (Last updated, Version 7)
Name MqnB
Scope(s) Bacteria
Template(s) A0LR22 (MQNB_ACIC1); Q5SKT7 (MQNB_THET8); Q9KXN0 (MQNB_STRCO); [ Recover all ]
Triggered by HAMAP; MF_00991 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier MQNB
Protein name RecName: Full=Futalosine hydrolase;
                 Short=FL hydrolase;
AltName: Full=Futalosine nucleosidase;
AltName: Full=Menaquinone biosynthetic enzyme MqnB;
Gene name Name=mqnB;

Comments [?]

FUNCTIONCatalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2).
CATALYTIC ACTIVITY Reaction=futalosine + H2O = dehypoxanthine futalosine + hypoxanthine; Xref=Rhea:RHEA:25904, ChEBI:CHEBI:15377, ChEBI:CHEBI:17368, ChEBI:CHEBI:58863, ChEBI:CHEBI:58864; EC=;
PATHWAYQuinol/quinone metabolism; menaquinone biosynthesis.
SIMILARITYBelongs to the PNP/UDP phosphorylase family. Futalosine hydrolase subfamily.

Keywords [?]

Gene Ontology [?]

GO:0016799; Molecular function:hydrolase activity, hydrolyzing N-glycosyl compounds
GO:0009234; Biological process:menaquinone biosynthetic process

Cross-references [?]

Pfam PF01048; PNP_UDP_1; 1;
NCBIfam TIGR03664; fut_nucase; 1;

Features [?]

Additional information [?]

Size range 175-387 amino acids
Related rules None
Fusion Nter: None Cter: None

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