HAMAP rule MF_00991

General rule information [?]

Accession	MF_00991
Dates	14-FEB-2014 (Created) 1-JUN-2023 (Last updated, Version 7)
Name	MqnB
Scope(s)	Bacteria
Template(s)	A0LR22 (MQNB_ACIC1); Q5SKT7 (MQNB_THET8); Q9KXN0 (MQNB_STRCO); [ Recover all ]
Triggered by	HAMAP; MF_00991 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier	MQNB
Protein name	RecName: Full=Futalosine hydrolase; Short=FL hydrolase; EC=3.2.2.26; AltName: Full=Futalosine nucleosidase; AltName: Full=Menaquinone biosynthetic enzyme MqnB;
Gene name	Name=mqnB;

Comments [?]

FUNCTION	Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2).
CATALYTIC ACTIVITY	Reaction=futalosine + H2O = dehypoxanthine futalosine + hypoxanthine; Xref=Rhea:RHEA:25904, ChEBI:CHEBI:15377, ChEBI:CHEBI:17368, ChEBI:CHEBI:58863, ChEBI:CHEBI:58864; EC=3.2.2.26;
PATHWAY	Quinol/quinone metabolism; menaquinone biosynthesis.
SIMILARITY	Belongs to the PNP/UDP phosphorylase family. Futalosine hydrolase subfamily.

Keywords [?]

Gene Ontology [?]

GO:0016799; Molecular function:hydrolase activity, hydrolyzing N-glycosyl compounds

GO:0009234; Biological process:menaquinone biosynthetic process

Cross-references [?]

Pfam	PF01048; PNP_UDP_1; 1;
NCBIfam	TIGR03664; fut_nucase; 1;

Features [?]

Additional information [?]