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HAMAP rule MF_00996

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General rule information [?]

Accession MF_00996
Dates 17-FEB-2014 (Created)
14-MAY-2022 (Last updated, Version 6)
Name MqnD
Templates Q5SI12 (MQND_THET8); Q9KXN1 (MQND_STRCO): [Recover all]

Propagated annotation [?]

Identifier, protein and gene names [?]

Protein name
RecName: Full=1,4-dihydroxy-6-naphtoate synthase;
EC 4.1.-.-;
AltName: Full=Menaquinone biosynthetic enzyme MqnD;
Gene name

Comments [?]

Function Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).
Pathway Quinol/quinone metabolism; menaquinone biosynthesis.
Similarity Belongs to the MqnA/MqnD family. MqnD subfamily.

Keywords [?]

Gene Ontology [?]

GO:0016830; Molecular function: carbon-carbon lyase activity.
GO:0009234; Biological process: menaquinone biosynthetic process.

Cross-references [?]

Pfam PF02621; VitK2_biosynth; 1;

Features [?]

From: MQND_THET8 (Q5SI12)
Key     From     To       Description   Tag   Condition   FTGroup
BINDING (Optional)     55     57       /ligand="substrate     K-[LIV]-S  
BINDING (Optional)     107     108       /ligand="substrate     [TS]-A  
ACT_SITE     145     145       Proton acceptor     H  

Additional information [?]

Size range 240-340 amino acids
Related rules None
Fusion None