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HAMAP rule MF_00996

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General rule information [?]

Accession MF_00996
Dates 17-FEB-2014 (Created)
14-MAY-2022 (Last updated, Version 6)
Name MqnD
Scope(s) Bacteria
Template(s) Q5SI12 (MQND_THET8); Q9KXN1 (MQND_STRCO); [ Recover all ]
Triggered by HAMAP; MF_00996 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier MQND
Protein name RecName: Full=1,4-dihydroxy-6-naphtoate synthase;
AltName: Full=Menaquinone biosynthetic enzyme MqnD;
Gene name Name=mqnD;

Comments [?]

FUNCTIONCatalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).
PATHWAYQuinol/quinone metabolism; menaquinone biosynthesis.
SIMILARITYBelongs to the MqnA/MqnD family. MqnD subfamily.

Keywords [?]

Gene Ontology [?]

GO:0016830; Molecular function:carbon-carbon lyase activity
GO:0009234; Biological process:menaquinone biosynthetic process

Cross-references [?]

Pfam PF02621; VitK2_biosynth; 1;

Features [?]

From: MQND_THET8 (Q5SI12)
Key From To Description Tag Condition FTGroup
BINDING 55 57 /ligand="substrate" K-[LIV]-S
BINDING 107 108 /ligand="substrate" [TS]-A
ACT_SITE 145 145 /note="Proton acceptor" H

Additional information [?]

Size range 240-340 amino acids
Related rules None
Fusion Nter: None Cter: None

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