HAMAP rule MF_00998
General rule information
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Accession | MF_00998 |
Dates | 31-MAR-2014 (Created)
5-JUL-2023 (Last updated, Version 9) |
Name | SQ_isomerase |
Scope(s) |
Bacteria Enterobacterales |
Template(s) | P32140 (SQUS_ECOLI); Q8ZKT7 (SQUS_SALTY); [ Recover all ] |
Triggered by |
HAMAP; MF_00998 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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Identifier | SQUS |
Protein name | RecName: Full=Sulfoquinovose isomerase; Short=SQ isomerase; EC=5.3.1.31; |
Comments
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FUNCTION | Catalyzes the isomerization of sulfoquinovose (SQ) to 6- deoxy-6-sulfo-D-fructose (SF). |
CATALYTIC ACTIVITY | Reaction=6-sulfo-beta-D-quinovose = 6-deoxy-6-sulfo-D-fructose; Xref=Rhea:RHEA:40439, ChEBI:CHEBI:77133, ChEBI:CHEBI:142957; EC=5.3.1.31; PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:40440; |
SUBUNIT | Homohexamer. |
SIMILARITY | Belongs to the N-acylglucosamine 2-epimerase family. |
Keywords
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Gene Ontology
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GO:0061593; Molecular function:sulfoquinovose isomerase activity |
GO:1902777; Biological process:6-sulfoquinovose(1-) catabolic process |
Cross-references
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Pfam | PF07221; GlcNAc_2-epim; 1; |
Features
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From: SQUS_SALTY (Q8ZKT7) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
ACT_SITE | 248 | 248 | /note="Proton donor/acceptor" | H | ||||||||
ACT_SITE | 383 | 383 | /note="Proton donor/acceptor" | H | ||||||||
BINDING | 55 | 55 | /ligand="6-sulfo-beta-D-quinovose" /ligand_id="ChEBI:CHEBI:142957" |
R | ||||||||
BINDING | 111 | 111 | /ligand="6-sulfo-beta-D-quinovose" /ligand_id="ChEBI:CHEBI:142957" |
Y | ||||||||
BINDING | 172 | 172 | /ligand="6-sulfo-beta-D-quinovose" /ligand_id="ChEBI:CHEBI:142957" |
N | ||||||||
BINDING | 176 | 176 | /ligand="6-sulfo-beta-D-quinovose" /ligand_id="ChEBI:CHEBI:142957" |
H | ||||||||
BINDING | 238 | 238 | /ligand="6-sulfo-beta-D-quinovose" /ligand_id="ChEBI:CHEBI:142957" |
R | ||||||||
BINDING | 251 | 251 | /ligand="6-sulfo-beta-D-quinovose" /ligand_id="ChEBI:CHEBI:142957" |
E | ||||||||
BINDING | 362 | 362 | /ligand="6-sulfo-beta-D-quinovose" /ligand_id="ChEBI:CHEBI:142957" |
Q | ||||||||
BINDING | 379 | 379 | /ligand="6-sulfo-beta-D-quinovose" /ligand_id="ChEBI:CHEBI:142957" |
Q | ||||||||
BINDING | 383 | 383 | /ligand="6-sulfo-beta-D-quinovose" /ligand_id="ChEBI:CHEBI:142957" |
H |
Additional information
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Size range | 390-420 amino acids |
Related rules |
None |
Fusion | Nter: None Cter: None |