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HAMAP rule MF_01000

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General rule information [?]

Accession MF_01000
Dates 12-FEB-2002 (Created)
19-NOV-2022 (Last updated, Version 31)
Name BtuF
Scope(s) Bacteria
Template(s) P37028 (BTUF_ECOLI); [ Recover all ]
Triggered by HAMAP; MF_01000 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier BTUF
Protein name RecName: Full=Vitamin B12-binding protein;
                 Flags: Precursor;
Gene name Name=btuF;

Comments [?]

FUNCTIONPart of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC.
SUBUNITThe complex is composed of two ATP-binding proteins (BtuD), two transmembrane proteins (BtuC) and a solute-binding protein (BtuF).
SIMILARITYBelongs to the BtuF family.

Keywords [?]

case <FT:5>
Disulfide bond
end case

Gene Ontology [?]

GO:0015889; Biological process:cobalamin transport
GO:0042597; Cellular component:periplasmic space

Cross-references [?]

Pfam PF01497; Peripla_BP_2; 1;
PROSITE PS50983; FE_B12_PBP; 1;
General Signal; -; 1;

Features [?]

From: BTUF_ECOLI (P37028)
Key From To Description Tag Condition FTGroup
BINDING 242 246 /ligand="cyanocob(III)alamin"
BINDING 50 50 /ligand="cyanocob(III)alamin"
SITE 72 72 /note="Important for BtuC binding" E
SITE 202 202 /note="Important for BtuC binding" E
DISULFID 183 259 C-x*-C

Additional information [?]

Size range 266-280 amino acids
Related rules None
Fusion Nter: None Cter: None

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