HAMAP rule MF_01000
General rule information
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| Accession | MF_01000 |
| Dates | 12-FEB-2002 (Created)
19-NOV-2022 (Last updated, Version 31) |
| Name | BtuF |
| Scope(s) |
Bacteria Enterobacterales Vibrionaceae |
| Template(s) | P37028 (BTUF_ECOLI); [ Recover all ] |
| Triggered by |
HAMAP; MF_01000 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | BTUF |
| Protein name | RecName: Full=Vitamin B12-binding protein; Flags: Precursor; |
| Gene name | Name=btuF; |
Comments
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| FUNCTION | Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC. |
| SUBUNIT | The complex is composed of two ATP-binding proteins (BtuD), two transmembrane proteins (BtuC) and a solute-binding protein (BtuF). |
| SUBCELLULAR LOCATION | Periplasm. |
| SIMILARITY | Belongs to the BtuF family. |
Keywords
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| case <FT:5> | |
| Disulfide bond | |
| end case | |
| Periplasm | |
| Signal | |
| Transport | |
Gene Ontology
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| GO:0015889; Biological process:cobalamin transport |
| GO:0042597; Cellular component:periplasmic space |
Cross-references
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Features
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| From: BTUF_ECOLI (P37028) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| BINDING | 242 | 246 | /ligand="cyanocob(III)alamin" /ligand_id="ChEBI:CHEBI:17439" |
D-W-F-E-R | ||||||||
| BINDING | 50 | 50 | /ligand="cyanocob(III)alamin" /ligand_id="ChEBI:CHEBI:17439" |
Y | ||||||||
| SITE | 72 | 72 | /note="Important for BtuC binding" | E | ||||||||
| SITE | 202 | 202 | /note="Important for BtuC binding" | E | ||||||||
| DISULFID | 183 | 259 | C-x*-C | |||||||||
Additional information
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| Size range | 266-280 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |