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HAMAP rule MF_01007

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General rule information [?]

Accession MF_01007
Dates 5-MAR-2002 (Created)
1-JUN-2023 (Last updated, Version 32)
Name 16SrRNA_methyltr_H
Scope(s) Bacteria
Template(s) P60390 (RSMH_ECOLI); Q9WZX6 (RSMH_THEMA); Q5SJD8 (RSMH_THET8); [ Recover all ]
Triggered by HAMAP; MF_01007 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier RSMH
Protein name RecName: Full=Ribosomal RNA small subunit methyltransferase H;
AltName: Full=16S rRNA m(4)C1402 methyltransferase;
AltName: Full=rRNA (cytosine-N(4)-)-methyltransferase RsmH;
Gene name Name=rsmH;

Comments [?]

FUNCTIONSpecifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
CATALYTIC ACTIVITY Reaction=cytidine(1402) in 16S rRNA + S-adenosyl-L-methionine = H(+) + N(4)-methylcytidine(1402) in 16S rRNA + S-adenosyl-L-homocysteine; Xref=Rhea:RHEA:42928, Rhea:RHEA-COMP:10286, Rhea:RHEA-COMP:10287, ChEBI:CHEBI:15378, ChEBI:CHEBI:57856, ChEBI:CHEBI:59789, ChEBI:CHEBI:74506, ChEBI:CHEBI:82748; EC=;
SIMILARITYBelongs to the methyltransferase superfamily. RsmH family.

Keywords [?]

Gene Ontology [?]

GO:0071424; Molecular function:rRNA (cytosine-N4-)-methyltransferase activity
GO:0070475; Biological process:rRNA base methylation
GO:0005737; Cellular component:cytoplasm

Cross-references [?]

Pfam PF01795; Methyltransf_5; 1;
PIRSF PIRSF004486; MraW; 1;
NCBIfam TIGR00006; TIGR00006; 1;

Features [?]

Key From To Description Tag Condition FTGroup
BINDING 36 38 /ligand="S-adenosyl-L-methionine"
BINDING 55 55 /ligand="S-adenosyl-L-methionine"
BINDING 82 82 /ligand="S-adenosyl-L-methionine"
BINDING 103 103 /ligand="S-adenosyl-L-methionine"
BINDING 110 110 /ligand="S-adenosyl-L-methionine"

Additional information [?]

Size range 283-396 amino acids
Related rules None
Fusion Nter: None Cter: None

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