HAMAP rule MF_01030
General rule information
[?]
| PURL | https://purl.expasy.org/hamap/rule/MF_01030 |
| Accession | MF_01030 |
| Dates | 28-FEB-2005 (Created)
03-SEP-2024 (Last updated, Version 23) |
| Name | D_Ser_dehydrat |
| Scope(s) |
Bacteria |
| Template(s) | P00926; [ Recover all ] |
| Triggered by |
HAMAP; MF_01030 (Get profile general information and statistics) |
Propagated annotation
[?]
Identifier, protein and gene names
[?]
| Identifier | SDHD |
| case <OC:Enterobacterales> | |
| Protein name | RecName: Full=D-serine dehydratase; EC=4.3.1.18; AltName: Full=D-serine deaminase; Short=DSD; |
| end case | |
| case not <OC:Enterobacterales> | |
| Protein name | RecName: Full=Probable D-serine dehydratase; EC=4.3.1.18; AltName: Full=D-serine deaminase; Short=DSD; |
| end case | |
| Gene name | Name=dsdA; |
Comments
[?]
| CATALYTIC ACTIVITY | Reaction=D-serine = pyruvate + NH4(+); Xref=Rhea:RHEA:13977, ChEBI:CHEBI:15361, ChEBI:CHEBI:28938, ChEBI:CHEBI:35247; EC=4.3.1.18; |
| COFACTOR | Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326; |
| case <OC:Enterobacterales> | |
| SUBUNIT | Monomer. |
| end case | |
| SIMILARITY | Belongs to the serine/threonine dehydratase family. DsdA subfamily. |
Keywords
[?]
Gene Ontology
[?]
| GO:0016836; Molecular function:hydro-lyase activity |
| GO:0046416; Biological process:D-amino acid metabolic process |
Cross-references
[?]
| Pfam | PF00291; PALP; 1; |
| PROSITE | PS00165; DEHYDRATASE_SER_THR; 1; |
| NCBIfam | TIGR02035; D_Ser_am_lyase; 1; |
Features
[?]
| From: SDHD_ECOLI (P00926) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| MOD_RES | 118 | 118 | /note="N6-(pyridoxal phosphate)lysine" | K | ||||||||
Additional information
[?]
| Size range | 422-459 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |
| Comments | Shorter N-terminus in SHIBS; sequence not included in alignment and not taken into account in size range. |