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HAMAP rule MF_01036

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General rule information [?]

Accession MF_01036
Dates 18-NOV-2002 (Created)
1-JUN-2023 (Last updated, Version 25)
Name RNase_II
Scope
Bacteria; Gammaproteobacteria
Template P30850 (RNB_ECOLI)

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
RNB
Protein name
RecName: Full=Exoribonuclease 2;
EC 3.1.13.1;
AltName: Full=Exoribonuclease II;
Short=RNase II;
Short=Ribonuclease II;
Gene name
rnb

Comments [?]

Function Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction.
Catalytic activity Reaction=Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates.; EC=3.1.13.1;
Subcellular location Cytoplasm.
Similarity Belongs to the RNR ribonuclease family. RNase II subfamily.

Keywords [?]


Gene Ontology [?]

GO:0008859; Molecular function: exoribonuclease II activity.
GO:0006402; Biological process: mRNA catabolic process.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

Pfam PF00575; S1; 1;
PF00773; RNB; 1;
NCBIfam TIGR00358; 3_prime_RNase; 1;
TIGR02062; RNase_B; 1;
PROSITE PS01175; RIBONUCLEASE_II; 1;
PS50126; S1; 1;

Features [?]

From: RNB_HAEIN (P44440)
Key     From     To       Description   Tag   Condition   FTGroup
DOMAIN     576     658       S1 motif        

Additional information [?]

Size range 644-678 amino acids
Related rules None
Fusion None