HAMAP rule MF_01036

General rule information [?]

Accession	MF_01036
Dates	18-NOV-2002 (Created) 1-JUN-2023 (Last updated, Version 25)

Name

RNase_II

Scope

Bacteria; Gammaproteobacteria

Template

P30850 (RNB_ECOLI)

Triggered by

HAMAP; MF_01036 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier

RNB

Protein name

RecName:		Full=Exoribonuclease 2;
		EC 3.1.13.1;
AltName:		Full=Exoribonuclease II;
		Short=RNase II;
		Short=Ribonuclease II;

Gene name

rnb

Comments [?]

Function	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction.
Catalytic activity	Reaction=Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates.; EC=3.1.13.1;
Subcellular location	Cytoplasm.
Similarity	Belongs to the RNR ribonuclease family. RNase II subfamily.

Keywords [?]

Cytoplasm
Hydrolase
Exonuclease
Nuclease
RNA-binding

Gene Ontology [?]

GO:0008859; Molecular function: exoribonuclease II activity.
GO:0006402; Biological process: mRNA catabolic process.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

Pfam	PF00575; S1; 1;
	PF00773; RNB; 1;
NCBIfam	TIGR00358; 3_prime_RNase; 1;
	TIGR02062; RNase_B; 1;
PROSITE	PS01175; RIBONUCLEASE_II; 1;
	PS50126; S1; 1;

Features [?]

From: RNB_HAEIN (P44440)

Key From To Description Tag Condition FTGroup

DOMAIN 576 658 S1 motif

Additional information [?]

Size range	644-678 amino acids
Related rules	None
Fusion	None

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