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HAMAP rule MF_01040

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General rule information [?]

Accession MF_01040
Dates 12-DEC-2002 (Created)
14-MAY-2022 (Last updated, Version 34)
Name PGAM_GpmB
Scope(s) Bacteria
Template(s) P62707 (GPMA_ECOLI); P0A7A2 (GPMB_ECOLI); [ Recover all ]
Triggered by HAMAP; MF_01040 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier GPMB
Protein name RecName: Full=Probable phosphoglycerate mutase GpmB;
AltName: Full=PGAM;
AltName: Full=Phosphoglyceromutase;
Gene name Name=gpmB;

Comments [?]

CATALYTIC ACTIVITY Reaction=(2R)-2-phosphoglycerate = (2R)-3-phosphoglycerate; Xref=Rhea:RHEA:15901, ChEBI:CHEBI:58272, ChEBI:CHEBI:58289;
PATHWAYCarbohydrate degradation; glycolysis; pyruvate from D- glyceraldehyde 3-phosphate: step 3/5.
SIMILARITYBelongs to the phosphoglycerate mutase family. GpmB subfamily.

Keywords [?]

Gene Ontology [?]

GO:0004619; Molecular function:phosphoglycerate mutase activity
GO:0006096; Biological process:glycolytic process

Cross-references [?]

Pfam PF00300; His_Phos_1; 1;

Features [?]

Key From To Description Tag Condition FTGroup
BINDING 8 15 /ligand="substrate" R-H-G-E-[TS]-x-W-N
BINDING 21 22 /ligand="substrate" Q-G
BINDING 82 85 /ligand="substrate" E-L-x-M
BINDING 104 105 /ligand="substrate" R-R
BINDING 151 152 /ligand="substrate" G-[IM]
ACT_SITE 9 9 /note="Tele-phosphohistidine intermediate" H
ACT_SITE 82 82 /note="Proton donor/acceptor" E
BINDING 58 58 /ligand="substrate" R
BINDING 60 60 /ligand="substrate" [RK]
SITE 150 150 /note="Transition state stabilizer" H

Additional information [?]

Size range 215-215 amino acids
Related rules MF_01039
Fusion Nter: None Cter: None

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