HAMAP rule MF_01040
General rule information
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| PURL | https://purl.expasy.org/hamap/rule/MF_01040 |
| Accession | MF_01040 |
| Dates | 12-DEC-2002 (Created)
14-MAY-2022 (Last updated, Version 34) |
| Name | PGAM_GpmB |
| Scope(s) |
Bacteria |
| Template(s) | P62707 (GPMA_ECOLI); P0A7A2 (GPMB_ECOLI); [ Recover all ] |
| Triggered by |
HAMAP; MF_01040 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | GPMB |
| Protein name | RecName: Full=Probable phosphoglycerate mutase GpmB; EC=5.4.2.-; AltName: Full=PGAM; AltName: Full=Phosphoglyceromutase; |
| Gene name | Name=gpmB; |
Comments
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| CATALYTIC ACTIVITY | Reaction=(2R)-2-phosphoglycerate = (2R)-3-phosphoglycerate; Xref=Rhea:RHEA:15901, ChEBI:CHEBI:58272, ChEBI:CHEBI:58289; |
| PATHWAY | Carbohydrate degradation; glycolysis; pyruvate from D- glyceraldehyde 3-phosphate: step 3/5. |
| SIMILARITY | Belongs to the phosphoglycerate mutase family. GpmB subfamily. |
Keywords
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Gene Ontology
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| GO:0004619; Molecular function:phosphoglycerate mutase activity |
| GO:0006096; Biological process:glycolytic process |
Cross-references
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Features
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| From: GPMB_ECOLI (P0A7A2) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| BINDING | 8 | 15 | /ligand="substrate" | R-H-G-E-[TS]-x-W-N | ||||||||
| BINDING | 21 | 22 | /ligand="substrate" | Q-G | ||||||||
| BINDING | 82 | 85 | /ligand="substrate" | E-L-x-M | ||||||||
| BINDING | 104 | 105 | /ligand="substrate" | R-R | ||||||||
| BINDING | 151 | 152 | /ligand="substrate" | G-[IM] | ||||||||
| ACT_SITE | 9 | 9 | /note="Tele-phosphohistidine intermediate" | H | ||||||||
| ACT_SITE | 82 | 82 | /note="Proton donor/acceptor" | E | ||||||||
| BINDING | 58 | 58 | /ligand="substrate" | R | ||||||||
| BINDING | 60 | 60 | /ligand="substrate" | [RK] | ||||||||
| SITE | 150 | 150 | /note="Transition state stabilizer" | H | ||||||||
Additional information
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| Size range | 215-215 amino acids |
| Related rules |
MF_01039 |
| Fusion | Nter: None Cter: None |