HAMAP rule MF_01051
General rule information
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| Accession | MF_01051 |
| Dates | 18-MAR-2003 (Created)
12-MAR-2024 (Last updated, Version 21) |
| Name | CaiD |
| Scope(s) |
Bacteria Enterobacterales |
| Template(s) | P31551 (CAID_ECOLI); Q8GB17 (CAID_PROSL); [ Recover all ] |
| Triggered by |
HAMAP; MF_01051 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | CAID |
| Protein name | RecName: Full=Carnitinyl-CoA dehydratase; EC=4.2.1.149; AltName: Full=Crotonobetainyl-CoA hydratase; |
| Gene name | Name=caiD; |
Comments
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| FUNCTION | Catalyzes the reversible dehydration of L-carnitinyl-CoA to crotonobetainyl-CoA. |
| CATALYTIC ACTIVITY | Reaction=(R)-carnitinyl-CoA = crotonobetainyl-CoA + H2O; Xref=Rhea:RHEA:28338, ChEBI:CHEBI:15377, ChEBI:CHEBI:60932, ChEBI:CHEBI:60933; EC=4.2.1.149; |
| PATHWAY | Amine and polyamine metabolism; carnitine metabolism. |
| SIMILARITY | Belongs to the enoyl-CoA hydratase/isomerase family. |
Keywords
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Gene Ontology
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| GO:0016836; Molecular function:hydro-lyase activity |
| GO:0009437; Biological process:carnitine metabolic process |
Cross-references
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Features
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| From: CAID_ECOLI (P31551) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| ACT_SITE | 111 | 111 | /note="Nucleophile" | E | ||||||||
| ACT_SITE | 131 | 131 | /note="Proton acceptor" | E | ||||||||
Additional information
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| Size range | 260-270 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |