HAMAP rule MF_01061

General rule information [?]

PURL	https://purl.expasy.org/hamap/rule/MF_01061
Accession	MF_01061
Dates	28-FEB-2005 (Created) 04-FEB-2025 (Last updated, Version 15)
Name	DnaT
Scope(s)	Bacteria Enterobacterales
Template(s)	P0A8J2; A6THX4; [ Recover all ]
Triggered by	HAMAP; MF_01061 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier	DNAT
Protein name	RecName: Full=Replication restart protein DnaT;
Gene name	Name=dnaT;

Comments [?]

FUNCTION	Involved in the restart of stalled replication forks, which reloads the replicative helicase on sites other than the origin of replication. Can function in multiple replication restart pathways. Displaces ssDNA from a PriB-ssDNA complex. Probably forms a spiral filament on ssDNA.
SUBUNIT	Homooligomerizes. Interacts with PriB. Component of the replication restart primosome. Primosome assembly occurs via a 'hand- off' mechanism. PriA binds to replication forks, subsequently PriB then DnaT bind; DnaT then displaces ssDNA to generate the helicase loading substrate.
SIMILARITY	Belongs to the DnaT family.

Keywords [?]

Gene Ontology [?]

GO:0003697; Molecular function:single-stranded DNA binding

GO:0006261; Biological process:DNA-templated DNA replication

GO:1990077; Cellular component:primosome complex

Cross-references [?]

Features [?]

Additional information [?]