HAMAP rule MF_01090
General rule information
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| Accession | MF_01090 |
| Dates | 27-NOV-2003 (Created)
1-JUN-2023 (Last updated, Version 19) |
| Name | HMD |
| Scope(s) |
Archaea |
| Template(s) | Q02394 (HMD_METKA); P32440 (HMD_METTM); Q50759 (HMD_METTL); [ Recover all ] |
| Triggered by |
HAMAP; MF_01090 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | HMD |
| Protein name | RecName: Full=5,10-methenyltetrahydromethanopterin hydrogenase; EC=1.12.98.2; AltName: Full=H(2)-dependent methylene-H(4)MPT dehydrogenase; AltName: Full=H(2)-forming N(5),N(10)-methylenetetrahydromethanopterin dehydrogenase; AltName: Full=N(5),N(10)-methenyltetrahydromethanopterin hydrogenase; |
| Gene name | Name=hmd; |
Comments
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| case <OC:Methanobacteria> or <OC:Methanococci> or <OC:Methanomicrobia> or <OC:Methanopyri> | |
| FUNCTION | Catalyzes the reversible reduction of methenyl-H(4)MPT(+) to methylene-H(4)MPT. |
| end case | |
| CATALYTIC ACTIVITY | Reaction=5,10-methenyl-5,6,7,8-tetrahydromethanopterin + H2 = 5,10- methylenetetrahydromethanopterin + H(+); Xref=Rhea:RHEA:20017, ChEBI:CHEBI:15378, ChEBI:CHEBI:18276, ChEBI:CHEBI:57818, ChEBI:CHEBI:58337; EC=1.12.98.2; |
| case <OC:Methanobacteria> or <OC:Methanococci> or <OC:Methanomicrobia> or <OC:Methanopyri> | |
| PATHWAY | One-carbon metabolism; methanogenesis from CO(2); 5,10- methylene-5,6,7,8-tetrahydromethanopterin from 5,10-methenyl-5,6,7,8- tetrahydromethanopterin (hydrogen route): step 1/1. |
| end case | |
| SIMILARITY | Belongs to the HMD family. |
Keywords
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| case <OC:Methanobacteria> or <OC:Methanococci> or <OC:Methanomicrobia> or <OC:Methanopyri> | |
| Methanogenesis | |
| end case | |
| One-carbon metabolism | |
| Oxidoreductase | |
Gene Ontology
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| GO:0047068; Molecular function:N5,N10-methenyltetrahydromethanopterin hydrogenase activity | |
| GO:0006730; Biological process:one-carbon metabolic process | |
| case <OCellular component:Methanobacteria> or <OC:Methanococci> or <OC:Methanomicrobia> or <OC:Methanopyri> | |
| GO:0015948; Biological process:methanogenesis | |
| end case | |
Cross-references
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Features
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Additional information
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| Size range | 343-358 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |