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Annotation rule MF_01090
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General rule information [?]

Accession MF_01090
Dates 27-NOV-2003 (Created)
19-NOV-2019 (Last updated, Version 18)
Name HMD
Scope
Archaea
Templates Q02394 (HMD_METKA); P32440 (HMD_METTM); Q50759 (HMD_METTL): [Recover all]

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
HMD
Protein name
RecName: Full=5,10-methenyltetrahydromethanopterin hydrogenase;
EC 1.12.98.2;
AltName: Full=H(2)-dependent methylene-H(4)MPT dehydrogenase;
AltName: Full=H(2)-forming N(5),N(10)-methylenetetrahydromethanopterin dehydrogenase;
AltName: Full=N(5),N(10)-methenyltetrahydromethanopterin hydrogenase;
Gene name
hmd

Comments [?]

case <OC:Methanobacteria> or <OC:Methanococci> or <OC:Methanomicrobia> or <OC:Methanopyri>
Function Catalyzes the reversible reduction of methenyl-H(4)MPT(+) to methylene-H(4)MPT.
end case
Catalytic activity RHEA:20017: 5,10-methenyl-5,6,7,8-tetrahydromethanopterin + H2 = 5,10-methylenetetrahydromethanopterin + H(+)
EC 1.12.98.2
case <OC:Methanobacteria> or <OC:Methanococci> or <OC:Methanomicrobia> or <OC:Methanopyri>
Pathway One-carbon metabolism; methanogenesis from CO(2); 5,10-methylene-5,6,7,8-tetrahydromethanopterin from 5,10-methenyl-5,6,7,8-tetrahydromethanopterin (hydrogen route): step 1/1.
end case
Similarity Belongs to the HMD family.

Keywords [?]

case <OC:Methanobacteria> or <OC:Methanococci> or <OC:Methanomicrobia> or <OC:Methanopyri>
end case

Gene Ontology [?]

GO:0047068; Molecular function: N5,N10-methenyltetrahydromethanopterin hydrogenase activity.
GO:0006730; Biological process: one-carbon metabolic process.
case <OC:Methanobacteria> or <OC:Methanococci> or <OC:Methanomicrobia> or <OC:Methanopyri>
GO:0015948; Biological process: methanogenesis.
end case

Cross-references [?]

Pfam PF03201; HMD; 1;
TIGRFAMs TIGR01723; hmd_TIGR; 1;

Additional information [?]

Size range 343-358 amino acids
Related rules None
Fusion None