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HAMAP rule MF_01132

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General rule information [?]

Accession MF_01132
Dates 2-FEB-2004 (Created)
1-JUN-2023 (Last updated, Version 26)
Name Spx
Scope(s) Bacteria
Template(s) O31602 (SPX_BACSU); Q2G1U6 (SPX_STAA8); [ Recover all ]
Triggered by HAMAP; MF_01132 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier SPX
Protein name RecName: Full=Global transcriptional regulator Spx;
Gene name Name=spx;

Comments [?]

FUNCTIONGlobal transcriptional regulator that plays a key role in stress response and exerts either positive or negative regulation of genes. Acts by interacting with the C-terminal domain of the alpha subunit of the RNA polymerase (RNAP). This interaction can enhance binding of RNAP to the promoter region of target genes and stimulate their transcription, or block interaction of RNAP with activator
SUBUNITInteracts with the C-terminal domain of the alpha subunit of the RNAP.
SIMILARITYBelongs to the ArsC family. Spx subfamily.

Keywords [?]

Gene Ontology [?]

GO:0006355; Biological process:regulation of DNA-templated transcription
GO:0005737; Cellular component:cytoplasm

Cross-references [?]

Pfam PF03960; ArsC; 1;
NCBIfam TIGR01617; arsC_related; 1;

Features [?]

From: SPX_BACSU (O31602)
Key From To Description Tag Condition FTGroup
DISULFID 10 13 /note="Redox-active" C-x-x-C

Additional information [?]

Size range 128-160 amino acids
Related rules None
Fusion Nter: None Cter: None

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