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HAMAP rule MF_01153

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General rule information [?]

Accession MF_01153
Dates 17-SEP-2004 (Created)
19-NOV-2019 (Last updated, Version 23)
Name DjlA
Scope
Bacteria; Gammaproteobacteria
Template P31680 (DJLA_ECOLI)
Triggered by

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
DJLA
Protein name
RecName: Full=Co-chaperone protein DjlA;
Gene name
djlA

Comments [?]

Function Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host.
Subunit Homodimer.
Subcellular location Cell inner membrane; Single-pass type III membrane protein.
Domain The transmembrane domain is a dimerization domain.

Keywords [?]

Chaperone
Membrane
Cell membrane
Cell inner membrane
Transmembrane
Transmembrane helix

Gene Ontology [?]

GO:0005886; Cellular component: plasma membrane.

Cross-references [?]

Pfam PF00226; DnaJ; 1;
PROSITE PS00636; DNAJ_1; 1;
PS50076; DNAJ_2; 1; trigger=PRU00286;

Features [?]

From: DJLA_ECOLI (P31680)
Key     From     To       Description   Tag   Condition   FTGroup
TOPO_DOM     Nter     6       Periplasmic        
TRANSMEM     7     31       Helical        
TOPO_DOM     32     Cter       Cytoplasmic        

Additional information [?]

Size range 250-330 amino acids
Related rules None
Fusion None


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