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HAMAP rule MF_01153

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General rule information [?]

Accession MF_01153
Dates 17-SEP-2004 (Created)
19-NOV-2019 (Last updated, Version 23)
Name DjlA
Scope(s) Bacteria
Template(s) P31680 (DJLA_ECOLI); [ Recover all ]
Triggered by HAMAP; MF_01153 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier DJLA
Protein name RecName: Full=Co-chaperone protein DjlA;
Gene name Name=djlA;

Comments [?]

FUNCTIONRegulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host.
SUBCELLULAR LOCATIONCell inner membrane; Single-pass type III membrane protein.
DOMAINThe transmembrane domain is a dimerization domain.

Keywords [?]

Gene Ontology [?]

GO:0005886; Cellular component:plasma membrane

Cross-references [?]

Pfam PF00226; DnaJ; 1;
PROSITE PS00636; DNAJ_1; 1;
PROSITE PS50076; DNAJ_2; 1;

Features [?]

From: DJLA_ECOLI (P31680)
Key From To Description Tag Condition FTGroup
TOPO_DOM Nter 6 /note="Periplasmic"
TRANSMEM 7 31 /note="Helical"
TOPO_DOM 32 Cter /note="Cytoplasmic"

Additional information [?]

Size range 250-330 amino acids
Related rules None
Fusion Nter: None Cter: None

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