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HAMAP rule MF_01160

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General rule information [?]

Accession MF_01160
Dates 22-FEB-2005 (Created)
19-NOV-2022 (Last updated, Version 19)
Name CutA
Scope(s) Bacteria
Enterobacterales
Template(s) P69488 (CUTA_ECOLI); [ Recover all ]
Triggered by HAMAP; MF_01160 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier CUTA
Protein name RecName: Full=Divalent-cation tolerance protein CutA;
Gene name Name=cutA;

Comments [?]

FUNCTIONInvolved in resistance toward heavy metals.
case <FTGroup:1>
COFACTOR Name=Cu cation; Xref=ChEBI:CHEBI:23378; Note=Binds 1 copper ion per subunit.;
end case
SUBUNITHomotrimer.
SUBCELLULAR LOCATIONCytoplasm.
SIMILARITYBelongs to the CutA family.

Keywords [?]

Cytoplasm
case <FTGroup:1>
Copper
Metal-binding
end case

Gene Ontology [?]

case <FTGroup:1>
GO:0005507; Molecular function:copper ion binding
end case
GO:0005737; Cellular component:cytoplasm

Cross-references [?]

Pfam PF03091; CutA1; 1;

Features [?]

From: CUTA_ECOLI (P69488)
Key From To Description Tag Condition FTGroup
BINDING 16 16 /ligand="Cu cation"
/ligand_id="ChEBI:CHEBI:23378"
C 1
BINDING 83 83 /ligand="Cu cation"
/ligand_id="ChEBI:CHEBI:23378"
H 1
BINDING 84 84 /ligand="Cu cation"
/ligand_id="ChEBI:CHEBI:23378"
H 1

Additional information [?]

Size range 100-126 amino acids
Related rules None
Fusion Nter: None Cter: None
Comments Similar sequences to cutA are found in several genomes. As the metal binding sites are not conserved in those and the function of this protein is currently unknown, we have therefore restricted this family to the Enterobacteriaceae.



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