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HAMAP rule MF_01160

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General rule information [?]

Accession MF_01160
Dates 22-FEB-2005 (Created)
19-NOV-2022 (Last updated, Version 19)
Name CutA
Bacteria; Enterobacterales
Template P69488 (CUTA_ECOLI)

Propagated annotation [?]

Identifier, protein and gene names [?]

Protein name
RecName: Full=Divalent-cation tolerance protein CutA;
Gene name

Comments [?]

Function Involved in resistance toward heavy metals.
case <FTGroup:1>
Cofactor Cu cation
Note: Binds 1 copper ion per subunit.
end case
Subunit Homotrimer.
Subcellular location Cytoplasm.
Similarity Belongs to the CutA family.

Keywords [?]

case <FTGroup:1>
end case

Gene Ontology [?]

case <FTGroup:1>
GO:0005507; Molecular function: copper ion binding.
end case
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

Pfam PF03091; CutA1; 1;

Features [?]

From: CUTA_ECOLI (P69488)
Key     From     To       Description   Tag   Condition   FTGroup
BINDING     16     16       /ligand="Cu cation" /ligand_id="ChEBI:CHEBI:23378     C   1
BINDING     83     83       /ligand="Cu cation" /ligand_id="ChEBI:CHEBI:23378     H   1
BINDING     84     84       /ligand="Cu cation" /ligand_id="ChEBI:CHEBI:23378     H   1

Additional information [?]

Size range 100-126 amino acids
Related rules None
Fusion None
Comments Similar sequences to cutA are found in several genomes. As the metal binding sites are not conserved in those and the function of this protein is currently unknown, we have therefore restricted this family to the Enterobacteriaceae.