HAMAP rule MF_01160
General rule information
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| Accession | MF_01160 |
| Dates | 22-FEB-2005 (Created) 19-NOV-2022 (Last updated, Version 19) |
| Name | CutA |
| Scope | Bacteria; Enterobacterales |
| Template | P69488 (CUTA_ECOLI) |
| Triggered by |
Propagated annotation
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Identifier, protein and gene names
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| Identifier |
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| Protein name |
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| Gene name |
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Comments
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| Function | Involved in resistance toward heavy metals. |
case <FTGroup:1>
| Cofactor | Cu cation Note: Binds 1 copper ion per subunit. |
end case
| Subunit | Homotrimer. |
| Subcellular location | Cytoplasm. |
| Similarity | Belongs to the CutA family. |
Keywords
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case <FTGroup:1>
end case
Gene Ontology
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case <FTGroup:1>
GO:0005507; Molecular function: copper ion binding.
end case
GO:0005737; Cellular component: cytoplasm.
Cross-references
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| Pfam | PF03091; CutA1; 1; |
Features
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| From: CUTA_ECOLI (P69488) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| BINDING | 16 | 16 | /ligand="Cu cation" /ligand_id="ChEBI:CHEBI:23378 | C | 1 | |||||||
| BINDING | 83 | 83 | /ligand="Cu cation" /ligand_id="ChEBI:CHEBI:23378 | H | 1 | |||||||
| BINDING | 84 | 84 | /ligand="Cu cation" /ligand_id="ChEBI:CHEBI:23378 | H | 1 | |||||||
Additional information
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| Size range | 100-126 amino acids |
| Related rules | None |
| Fusion | None |
| Comments | Similar sequences to cutA are found in several genomes. As the metal binding sites are not conserved in those and the function of this protein is currently unknown, we have therefore restricted this family to the Enterobacteriaceae. |