HAMAP rule MF_01160
General rule information
[?]
Accession | MF_01160 |
Dates | 22-FEB-2005 (Created)
19-NOV-2022 (Last updated, Version 19) |
Name | CutA |
Scope(s) |
Bacteria Enterobacterales |
Template(s) | P69488 (CUTA_ECOLI); [ Recover all ] |
Triggered by |
HAMAP; MF_01160 (Get profile general information and statistics) |
Propagated annotation
[?]
Identifier, protein and gene names
[?]
Identifier | CUTA |
Protein name | RecName: Full=Divalent-cation tolerance protein CutA; |
Gene name | Name=cutA; |
Comments
[?]
FUNCTION | Involved in resistance toward heavy metals. |
case <FTGroup:1> | |
COFACTOR | Name=Cu cation; Xref=ChEBI:CHEBI:23378; Note=Binds 1 copper ion per subunit.; |
end case | |
SUBUNIT | Homotrimer. |
SUBCELLULAR LOCATION | Cytoplasm. |
SIMILARITY | Belongs to the CutA family. |
Keywords
[?]
Cytoplasm | |
case <FTGroup:1> | |
Copper | |
Metal-binding | |
end case |
Gene Ontology
[?]
case <FTGroup:1> | |
GO:0005507; Molecular function:copper ion binding | |
end case | |
GO:0005737; Cellular component:cytoplasm |
Cross-references
[?]
Pfam | PF03091; CutA1; 1; |
Features
[?]
From: CUTA_ECOLI (P69488) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
BINDING | 16 | 16 | /ligand="Cu cation" /ligand_id="ChEBI:CHEBI:23378" |
C | 1 | |||||||
BINDING | 83 | 83 | /ligand="Cu cation" /ligand_id="ChEBI:CHEBI:23378" |
H | 1 | |||||||
BINDING | 84 | 84 | /ligand="Cu cation" /ligand_id="ChEBI:CHEBI:23378" |
H | 1 |
Additional information
[?]
Size range | 100-126 amino acids |
Related rules |
None |
Fusion | Nter: None Cter: None |
Comments | Similar sequences to cutA are found in several genomes. As the metal binding sites are not conserved in those and the function of this protein is currently unknown, we have therefore restricted this family to the Enterobacteriaceae. |