HAMAP rule MF_01170
General rule information
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| PURL | https://purl.expasy.org/hamap/rule/MF_01170 |
| Accession | MF_01170 |
| Dates | 06-FEB-2006 (Created)
19-NOV-2019 (Last updated, Version 16) |
| Name | RacA |
| Scope(s) |
Bacteria Bacillales |
| Template(s) | P45870; [ Recover all ] |
| Triggered by |
HAMAP; MF_01170 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | RACA |
| Protein name | RecName: Full=Chromosome-anchoring protein RacA; |
| Gene name | Name=racA; |
Comments
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| FUNCTION | Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure. |
| SUBCELLULAR LOCATION | Cytoplasm. Note=Localizes to cell poles and nucleoid. |
| SIMILARITY | Belongs to the RacA family. |
Keywords
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Gene Ontology
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| GO:0003690; Molecular function:double-stranded DNA binding |
| GO:0008356; Biological process:asymmetric cell division |
| GO:0030261; Biological process:chromosome condensation |
| GO:0007059; Biological process:chromosome segregation |
| GO:0030435; Biological process:sporulation resulting in formation of a cellular spore |
| GO:0005737; Cellular component:cytoplasm |
Cross-references
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| Pfam | PF00376; MerR; 1; |
| General | Coiled_coil; -; 0-unlimited; |
Features
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| From: RACA_BACSU (P45870) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DNA_BIND | 3 | 23 | /note="H-T-H motif" | |||||||||
Additional information
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| Size range | 171-216 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |