HAMAP rule MF_01171

General rule information [?]

PURL	https://purl.expasy.org/hamap/rule/MF_01171
Accession	MF_01171
Dates	06-NOV-2006 (Created) 03-SEP-2024 (Last updated, Version 21)
Name	AstA
Scope(s)	Bacteria Enterobacterales
Template(s)	P0AE37; [ Recover all ]
Triggered by	HAMAP; MF_01171 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier	ASTA
Protein name	RecName: Full=Arginine N-succinyltransferase; Short=AST; EC=2.3.1.109; AltName: Full=AOST;
Gene name	Name=astA;

Comments [?]

FUNCTION	Catalyzes the transfer of succinyl-CoA to arginine to produce N(2)-succinylarginine.
CATALYTIC ACTIVITY	Reaction=succinyl-CoA + L-arginine = N(2)-succinyl-L-arginine + CoA + H(+); Xref=Rhea:RHEA:15185, ChEBI:CHEBI:15378, ChEBI:CHEBI:32682, ChEBI:CHEBI:57287, ChEBI:CHEBI:57292, ChEBI:CHEBI:58241; EC=2.3.1.109;
PATHWAY	Amino-acid degradation; L-arginine degradation via AST pathway; L-glutamate and succinate from L-arginine: step 1/5.
SIMILARITY	Belongs to the arginine N-succinyltransferase family.

Keywords [?]

Gene Ontology [?]

GO:0008791; Molecular function:arginine N-succinyltransferase activity

GO:0019544; Biological process:arginine catabolic process to glutamate

GO:0019545; Biological process:arginine catabolic process to succinate

Cross-references [?]

Pfam	PF04958; AstA; 1;
NCBIfam	TIGR03244; arg_catab_AstA; 1;

Features [?]

From: ASTA_ECOLI (P0AE37)

Key

From

Description

Tag

Condition

FTGroup

ACT_SITE

229

/note="Proton donor"

BINDING

125

/ligand="succinyl-CoA"
/ligand_id="ChEBI:CHEBI:57292"

Additional information [?]