HAMAP rule MF_01172
General rule information
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Accession | MF_01172 |
Dates | 3-NOV-2006 (Created) 1-JUN-2023 (Last updated, Version 22) |
Name | AstB |
Scope | Bacteria; Pseudomonadota |
Template | P76216 (ASTB_ECOLI) |
Triggered by |
Propagated annotation
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Identifier, protein and gene names
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Identifier |
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Protein name |
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Gene name |
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Comments
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Function | Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2). |
Catalytic activity | RHEA:19533: 2 H(+) + 2 H2O + N(2)-succinyl-L-arginine = CO2 + N(2)-succinyl-L-ornithine + 2 NH4(+)
EC 3.5.3.23 |
Pathway | Amino-acid degradation; L-arginine degradation via AST pathway; L-glutamate and succinate from L-arginine: step 2/5. |
Subunit | Homodimer. |
Similarity | Belongs to the succinylarginine dihydrolase family. |
Keywords
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Gene Ontology
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GO:0009015; Molecular function: N-succinylarginine dihydrolase activity.
GO:0019544; Biological process: arginine catabolic process to glutamate.
GO:0019544; Biological process: arginine catabolic process to glutamate.
Cross-references
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Features
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From: ASTB_ECOLI (P76216) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
BINDING | 19 | 28 | /ligand="substrate | |||||||||
BINDING | 137 | 138 | /ligand="substrate | |||||||||
ACT_SITE | 174 | 174 | E | |||||||||
ACT_SITE | 248 | 248 | H | |||||||||
ACT_SITE | 365 | 365 | Nucleophile | C | ||||||||
BINDING | 110 | 110 | /ligand="substrate | N | ||||||||
BINDING | 212 | 212 | /ligand="substrate | R | ||||||||
BINDING | 250 | 250 | /ligand="substrate | D | ||||||||
BINDING | 359 | 359 | /ligand="substrate | N |
Additional information
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Size range | 415-449 amino acids |
Related rules | None |
Fusion | None |