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Annotation rule MF_01172
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General rule information [?]

Accession MF_01172
Dates 3-NOV-2006 (Created)
19-NOV-2019 (Last updated, Version 18)
Name AstB
Scope
Bacteria; Proteobacteria
Template P76216 (ASTB_ECOLI)
Triggered by

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
ASTB
Protein name
RecName: Full=N-succinylarginine dihydrolase;
EC 3.5.3.23;
Gene name
astB

Comments [?]

Function Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2).
Catalytic activity RHEA:19533: 2 H(+) + 2 H2O + N(2)-succinyl-L-arginine = CO2 + N(2)-succinyl-L-ornithine + 2 NH4(+)
EC 3.5.3.23
Pathway Amino-acid degradation; L-arginine degradation via AST pathway; L-glutamate and succinate from L-arginine: step 2/5.
Subunit Homodimer.
Similarity Belongs to the succinylarginine dihydrolase family.

Keywords [?]

Arginine metabolism
Hydrolase

Gene Ontology [?]

GO:0009015; Molecular function: N-succinylarginine dihydrolase activity.
GO:0019544; Biological process: arginine catabolic process to glutamate.

Cross-references [?]

Pfam PF04996; AstB; 1;
TIGRFAMs TIGR03241; arg_catab_astB; 1;

Features [?]

From: ASTB_ECOLI (P76216)
Key     From     To       Description   Tag   Condition   FTGroup
REGION     19     28       Substrate binding        
REGION     137     138       Substrate binding        
ACT_SITE     174     174             E  
ACT_SITE     248     248             H  
ACT_SITE     365     365       Nucleophile     C  
BINDING     110     110       Substrate     N  
BINDING     212     212       Substrate     R  
BINDING     250     250       Substrate     D  
BINDING     359     359       Substrate     N  

Additional information [?]

Size range 415-449 amino acids
Related rules None
Fusion None


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