HAMAP rule MF_01172

General rule information [?]

Accession	MF_01172
Dates	3-NOV-2006 (Created) 1-JUN-2023 (Last updated, Version 22)

Name

AstB

Scope

Bacteria; Pseudomonadota

Template

P76216 (ASTB_ECOLI)

Triggered by

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier

ASTB

Protein name

RecName:		Full=N-succinylarginine dihydrolase;
		EC 3.5.3.23;

Gene name

astB

Comments [?]

Function	Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2).
Catalytic activity	RHEA:19533: 2 H(+) + 2 H2O + N(2)-succinyl-L-arginine = CO2 + N(2)-succinyl-L-ornithine + 2 NH4(+) EC 3.5.3.23
Pathway	Amino-acid degradation; L-arginine degradation via AST pathway; L-glutamate and succinate from L-arginine: step 2/5.
Subunit	Homodimer.
Similarity	Belongs to the succinylarginine dihydrolase family.

Keywords [?]

Gene Ontology [?]

GO:0009015; Molecular function: N-succinylarginine dihydrolase activity.
GO:0019544; Biological process: arginine catabolic process to glutamate.

Cross-references [?]

Pfam	PF04996; AstB; 1;
NCBIfam	TIGR03241; arg_catab_astB; 1;

Features [?]

From: ASTB_ECOLI (P76216)

Key From To Description Tag Condition FTGroup

BINDING 19 28 /ligand="substrate

BINDING 137 138 /ligand="substrate

ACT_SITE 174 174 E

ACT_SITE 248 248 H

ACT_SITE 365 365 Nucleophile C

BINDING 110 110 /ligand="substrate N

BINDING 212 212 /ligand="substrate R

BINDING 250 250 /ligand="substrate D

BINDING 359 359 /ligand="substrate N

Additional information [?]