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HAMAP rule MF_01172

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General rule information [?]

Accession MF_01172
Dates 3-NOV-2006 (Created)
1-JUN-2023 (Last updated, Version 22)
Name AstB
Scope(s) Bacteria
Template(s) P76216 (ASTB_ECOLI); [ Recover all ]
Triggered by HAMAP; MF_01172 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier ASTB
Protein name RecName: Full=N-succinylarginine dihydrolase;
Gene name Name=astB;

Comments [?]

FUNCTIONCatalyzes the hydrolysis of N(2)-succinylarginine into N(2)- succinylornithine, ammonia and CO(2).
CATALYTIC ACTIVITY Reaction=2 H(+) + 2 H2O + N(2)-succinyl-L-arginine = CO2 + N(2)- succinyl-L-ornithine + 2 NH4(+); Xref=Rhea:RHEA:19533, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:16526, ChEBI:CHEBI:28938, ChEBI:CHEBI:58241, ChEBI:CHEBI:58514; EC=;
PATHWAYAmino-acid degradation; L-arginine degradation via AST pathway; L-glutamate and succinate from L-arginine: step 2/5.
SIMILARITYBelongs to the succinylarginine dihydrolase family.

Keywords [?]

Gene Ontology [?]

GO:0009015; Molecular function:N-succinylarginine dihydrolase activity
GO:0019544; Biological process:arginine catabolic process to glutamate

Cross-references [?]

Pfam PF04996; AstB; 1;
NCBIfam TIGR03241; arg_catab_astB; 1;

Features [?]

From: ASTB_ECOLI (P76216)
Key From To Description Tag Condition FTGroup
BINDING 19 28 /ligand="substrate"
BINDING 137 138 /ligand="substrate"
ACT_SITE 174 174 E
ACT_SITE 248 248 H
ACT_SITE 365 365 /note="Nucleophile" C
BINDING 110 110 /ligand="substrate" N
BINDING 212 212 /ligand="substrate" R
BINDING 250 250 /ligand="substrate" D
BINDING 359 359 /ligand="substrate" N

Additional information [?]

Size range 415-449 amino acids
Related rules None
Fusion Nter: None Cter: None

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