HAMAP rule MF_01173

General rule information [?]

Accession	MF_01173
Dates	9-NOV-2006 (Created) 1-JUN-2023 (Last updated, Version 17)

Name	AstC_aminotrans_3

Scope

Bacteria; Enterobacterales

Template

P77581 (ASTC_ECOLI)

Triggered by

HAMAP; MF_01173 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier

ASTC

Protein name

RecName:		Full=Succinylornithine transaminase;
		EC 2.6.1.81;
AltName:		Full=Succinylornithine aminotransferase;

Gene name

astC, argM

Comments [?]

Function	Catalyzes the transamination of N(2)-succinylornithine and alpha-ketoglutarate into N(2)-succinylglutamate semialdehyde and glutamate. Can also act as an acetylornithine aminotransferase.
Catalytic activity	RHEA:16953: 2-oxoglutarate + N(2)-succinyl-L-ornithine = L-glutamate + N-succinyl-L-glutamate 5-semialdehyde EC 2.6.1.81
Cofactor	pyridoxal 5'-phosphate
Pathway	Amino-acid degradation; L-arginine degradation via AST pathway; L-glutamate and succinate from L-arginine: step 3/5.
Similarity	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. AstC subfamily.

Keywords [?]

Aminotransferase
Arginine metabolism
Pyridoxal phosphate
Transferase

Gene Ontology [?]

GO:0030170; Molecular function: pyridoxal phosphate binding.
GO:0008483; Molecular function: transaminase activity.
GO:0019544; Biological process: arginine catabolic process to glutamate.

Cross-references [?]

PROSITE	PS00600; AA_TRANSFER_CLASS_3; 1;
Pfam	PF00202; Aminotran_3; 1;
NCBIfam	TIGR00707; ArgD; 1;

Features [?]

From: ASTC_ECOLI (P77581)

Key From To Description Tag Condition FTGroup

MOD_RES 252 252 N6-(pyridoxal phosphate)lysine K

Additional information [?]

Size range	402-414 amino acids
Related rules	MF_01107 (ARGD)
Fusion	None

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