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HAMAP rule MF_01173

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General rule information [?]

Accession MF_01173
Dates 9-NOV-2006 (Created)
1-JUN-2023 (Last updated, Version 17)
Name AstC_aminotrans_3
Scope
Bacteria; Enterobacterales
Template P77581 (ASTC_ECOLI)

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
ASTC
Protein name
RecName: Full=Succinylornithine transaminase;
EC 2.6.1.81;
AltName: Full=Succinylornithine aminotransferase;
Gene name
astC, argM

Comments [?]

Function Catalyzes the transamination of N(2)-succinylornithine and alpha-ketoglutarate into N(2)-succinylglutamate semialdehyde and glutamate. Can also act as an acetylornithine aminotransferase.
Catalytic activity RHEA:16953: 2-oxoglutarate + N(2)-succinyl-L-ornithine = L-glutamate + N-succinyl-L-glutamate 5-semialdehyde
EC 2.6.1.81
Cofactor pyridoxal 5'-phosphate
Pathway Amino-acid degradation; L-arginine degradation via AST pathway; L-glutamate and succinate from L-arginine: step 3/5.
Similarity Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. AstC subfamily.

Keywords [?]


Gene Ontology [?]

GO:0030170; Molecular function: pyridoxal phosphate binding.
GO:0008483; Molecular function: transaminase activity.
GO:0019544; Biological process: arginine catabolic process to glutamate.

Cross-references [?]

PROSITE PS00600; AA_TRANSFER_CLASS_3; 1;
Pfam PF00202; Aminotran_3; 1;
NCBIfam TIGR00707; ArgD; 1;

Features [?]

From: ASTC_ECOLI (P77581)
Key     From     To       Description   Tag   Condition   FTGroup
MOD_RES     252     252       N6-(pyridoxal phosphate)lysine     K  

Additional information [?]

Size range 402-414 amino acids
Related rules MF_01107 (ARGD)
Fusion None