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HAMAP rule MF_01173

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General rule information [?]

Accession MF_01173
Dates 9-NOV-2006 (Created)
1-JUN-2023 (Last updated, Version 17)
Name AstC_aminotrans_3
Scope(s) Bacteria
Template(s) P77581 (ASTC_ECOLI); [ Recover all ]
Triggered by HAMAP; MF_01173 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier ASTC
Protein name RecName: Full=Succinylornithine transaminase;
AltName: Full=Succinylornithine aminotransferase;
Gene name Name=astC; Synonyms=argM;

Comments [?]

FUNCTIONCatalyzes the transamination of N(2)-succinylornithine and alpha-ketoglutarate into N(2)-succinylglutamate semialdehyde and glutamate. Can also act as an acetylornithine aminotransferase.
CATALYTIC ACTIVITY Reaction=2-oxoglutarate + N(2)-succinyl-L-ornithine = L-glutamate + N- succinyl-L-glutamate 5-semialdehyde; Xref=Rhea:RHEA:16953, ChEBI:CHEBI:16810, ChEBI:CHEBI:29985, ChEBI:CHEBI:58514, ChEBI:CHEBI:58520; EC=;
COFACTOR Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
PATHWAYAmino-acid degradation; L-arginine degradation via AST pathway; L-glutamate and succinate from L-arginine: step 3/5.
SIMILARITYBelongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. AstC subfamily.

Keywords [?]

Gene Ontology [?]

GO:0030170; Molecular function:pyridoxal phosphate binding
GO:0008483; Molecular function:transaminase activity
GO:0019544; Biological process:arginine catabolic process to glutamate

Cross-references [?]

Pfam PF00202; Aminotran_3; 1;
NCBIfam TIGR00707; ArgD; 1;

Features [?]

From: ASTC_ECOLI (P77581)
Key From To Description Tag Condition FTGroup
MOD_RES 252 252 /note="N6-(pyridoxal phosphate)lysine" K

Additional information [?]

Size range 402-414 amino acids
Related rules MF_01107
Fusion Nter: None Cter: None

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