HAMAP rule MF_01173
General rule information
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| PURL | https://purl.expasy.org/hamap/rule/MF_01173 |
| Accession | MF_01173 |
| Dates | 09-NOV-2006 (Created)
03-SEP-2024 (Last updated, Version 20) |
| Name | AstC_aminotrans_3 |
| Scope(s) |
Bacteria Enterobacterales |
| Template(s) | P77581; [ Recover all ] |
| Triggered by |
HAMAP; MF_01173 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | ASTC |
| Protein name | RecName: Full=Succinylornithine transaminase; EC=2.6.1.81; AltName: Full=Succinylornithine aminotransferase; |
| Gene name | Name=astC; Synonyms=argM; |
Comments
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| FUNCTION | Catalyzes the transamination of N(2)-succinylornithine and alpha-ketoglutarate into N(2)-succinylglutamate semialdehyde and glutamate. Can also act as an acetylornithine aminotransferase. |
| CATALYTIC ACTIVITY | Reaction=N(2)-succinyl-L-ornithine + 2-oxoglutarate = N-succinyl-L- glutamate 5-semialdehyde + L-glutamate; Xref=Rhea:RHEA:16953, ChEBI:CHEBI:16810, ChEBI:CHEBI:29985, ChEBI:CHEBI:58514, ChEBI:CHEBI:58520; EC=2.6.1.81; |
| COFACTOR | Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326; |
| PATHWAY | Amino-acid degradation; L-arginine degradation via AST pathway; L-glutamate and succinate from L-arginine: step 3/5. |
| SIMILARITY | Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. AstC subfamily. |
Keywords
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Gene Ontology
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| GO:0030170; Molecular function:pyridoxal phosphate binding |
| GO:0008483; Molecular function:transaminase activity |
| GO:0019544; Biological process:arginine catabolic process to glutamate |
| GO:0019545; Biological process:arginine catabolic process to succinate |
Cross-references
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Features
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| From: ASTC_ECOLI (P77581) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| MOD_RES | 252 | 252 | /note="N6-(pyridoxal phosphate)lysine" | K | ||||||||
Additional information
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| Size range | 402-414 amino acids |
| Related rules |
MF_01107 |
| Fusion | Nter: None Cter: None |