HAMAP rule MF_01178
General rule information
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| PURL | https://purl.expasy.org/hamap/rule/MF_01178 |
| Accession | MF_01178 |
| Dates | 24-NOV-2006 (Created)
29-JUN-2022 (Last updated, Version 17) |
| Name | Crl |
| Scope(s) |
Bacteria Gammaproteobacteria |
| Template(s) | P24251; [ Recover all ] |
| Triggered by |
HAMAP; MF_01178 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | CRL |
| Protein name | RecName: Full=Sigma factor-binding protein Crl; |
| Gene name | Name=crl; |
Comments
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| FUNCTION | Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32. |
| SUBCELLULAR LOCATION | Cytoplasm. |
| SIMILARITY | Belongs to the Crl family. |
Keywords
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Gene Ontology
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| GO:0045893; Biological process:positive regulation of DNA-templated transcription |
| GO:0005737; Cellular component:cytoplasm |
Cross-references
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| Pfam | PF07417; Crl; 1; |
| General | Coiled_coil; -; 0-unlimited; |
Features
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| From: CRL_ECOLI (P24251) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| REGION | 99 | 122 | /note="Essential for activity" | |||||||||
Additional information
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| Size range | 113-165 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |