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HAMAP rule MF_01217

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General rule information [?]

Accession MF_01217
Dates 26-JUN-2002 (Created)
19-NOV-2019 (Last updated, Version 37)
Name Acyl_carrier
Scope
Bacteria
Plastid
Templates P0A6A8 (ACP_ECOLI); P80643 (ACP_BACSU); P20803 (ACP_ANAVA); P94123 (ACP_AZOBR); O54439 (ACP1_PSEAE); Q9RG22 (ACP_RHILE); P19372 (ACP_RHIME); P12784 (ACP_CERSP); P11830 (ACP_SACEN); P20804 (ACP_SYNY3): [Recover all]
Triggered by

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
ACP
Protein name
RecName: Full=Acyl carrier protein;
Short=ACP;
Gene name
acpP

Comments [?]

Function Carrier of the growing fatty acid chain in fatty acid biosynthesis.
Pathway Lipid metabolism; fatty acid biosynthesis.
case <OG:Chloroplast>
Subcellular location Plastid, chloroplast.
end case
case not <OG:Chloroplast>
Subcellular location Cytoplasm.
end case
Ptm 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
Similarity Belongs to the acyl carrier protein (ACP) family.

Keywords [?]

case not <OG:Chloroplast>
Cytoplasm
end case
Fatty acid biosynthesis
Fatty acid metabolism
Lipid biosynthesis
Lipid metabolism
Phosphopantetheine
Phosphoprotein

Gene Ontology [?]

GO:0000036; Molecular function: acyl carrier activity.
GO:0006633; Biological process: fatty acid biosynthetic process.
case <OG:Chloroplast>
GO:0009507; Cellular component: chloroplast.
end case
case not <OG:Chloroplast>
GO:0005737; Cellular component: cytoplasm.
end case

Cross-references [?]

Pfam PF00550; PP-binding; 1;
TIGRFAMs TIGR00517; Acyl_carrier; 1;
PROSITE PS00012; PHOSPHOPANTETHEINE; 1;
PS50075; CARRIER; 1; trigger=PRU00258;

Features [?]

From: ACP_ECOLI (P0A6A8)
Key     From     To       Description   Tag   Condition   FTGroup
MOD_RES     37     37       O-(pantetheine 4'-phosphoryl)serine     S  

Additional information [?]

Size range 69-95 amino acids
Related rules None
Fusion None
Comments Longer C-terminal in MYCTU, MYCLE and in the second copy in CLOAB; sequences not shown in alignment and not taken into account in size range. Longer sequence in CYAPA; not shown in alignment and not taken into account in size range.


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