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| Annotation rule MF_01217 |
General rule information
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| Accession | MF_01217 |
| Dates | 26-JUN-2002 (Created) 19-NOV-2019 (Last updated, Version 37) |
| Name | Acyl_carrier |
| Scope | Bacteria
Plastid |
| Templates | P0A6A8 (ACP_ECOLI); P80643 (ACP_BACSU); P20803 (ACP_ANAVA); P94123 (ACP_AZOBR); O54439 (ACP1_PSEAE); Q9RG22 (ACP_RHILE); P19372 (ACP_RHIME); P12784 (ACP_CERSP); P11830 (ACP_SACEN); P20804 (ACP_SYNY3): [Recover all] |
| Triggered by |
Propagated annotation
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Identifier, protein and gene names
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| Identifier |
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| Protein name |
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| Gene name |
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Comments
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| Function | Carrier of the growing fatty acid chain in fatty acid biosynthesis. |
| Pathway | Lipid metabolism; fatty acid biosynthesis. |
case <OG:Chloroplast>
| Subcellular location | Plastid, chloroplast. |
end case
case not <OG:Chloroplast>
| Subcellular location | Cytoplasm. |
end case
| Ptm | 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group. |
| Similarity | Belongs to the acyl carrier protein (ACP) family. |
Keywords
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case not <OG:Chloroplast>
end case
Fatty acid biosynthesis
Fatty acid metabolism
Lipid biosynthesis
Lipid metabolism
Phosphopantetheine
Phosphoprotein
Fatty acid metabolism
Lipid biosynthesis
Lipid metabolism
Phosphopantetheine
Phosphoprotein
Gene Ontology
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GO:0000036; Molecular function: acyl carrier activity.
GO:0006633; Biological process: fatty acid biosynthetic process.
GO:0006633; Biological process: fatty acid biosynthetic process.
case <OG:Chloroplast>
GO:0009507; Cellular component: chloroplast.
end case
case not <OG:Chloroplast>
GO:0005737; Cellular component: cytoplasm.
end case
Cross-references
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| Pfam | PF00550; PP-binding; 1; |
| TIGRFAMs | TIGR00517; Acyl_carrier; 1; |
| PROSITE | PS00012; PHOSPHOPANTETHEINE; 1; |
| PS50075; CARRIER; 1; trigger=PRU00258; |
Features
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| From: ACP_ECOLI (P0A6A8) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| MOD_RES | 37 | 37 | O-(pantetheine 4'-phosphoryl)serine | S | ||||||||
Additional information
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| Size range | 69-95 amino acids |
| Related rules | None |
| Fusion | None |
| Comments | Longer C-terminal in MYCTU, MYCLE and in the second copy in CLOAB; sequences not shown in alignment and not taken into account in size range. Longer sequence in CYAPA; not shown in alignment and not taken into account in size range. |