HAMAP rule MF_01222

General rule information [?]

PURL	https://purl.expasy.org/hamap/rule/MF_01222
Accession	MF_01222
Dates	28-FEB-2005 (Created) 19-NOV-2022 (Last updated, Version 19)
Name	Archease_arch
Scope(s)	Bacteria Archaea
Template(s)	Q9V105; O59205; [ Recover all ]
Triggered by	HAMAP; MF_01222 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier	ARCH
Protein name	RecName: Full=Protein archease;

Comments [?]

FUNCTION	Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently.
SIMILARITY	Belongs to the archease family.

Keywords [?]

Gene Ontology [?]

GO:0005509; Molecular function:calcium ion binding

GO:0006388; Biological process:tRNA splicing, via endonucleolytic cleavage and ligation

Cross-references [?]

Pfam	PF01951; Archease; 1;

Features [?]

From: ARCH_PYRHO (O59205)

Key

From

Description

Tag

Condition

FTGroup

BINDING

/ligand="Ca(2+)"
/ligand_id="ChEBI:CHEBI:29108"

BINDING

141

/ligand="Ca(2+)"
/ligand_id="ChEBI:CHEBI:29108"

BINDING

Cter

/ligand="Ca(2+)"
/ligand_id="ChEBI:CHEBI:29108"

[ILVT]

Additional information [?]