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HAMAP rule MF_01222

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General rule information [?]

Accession MF_01222
Dates 2-SEP-2002 (Created)
19-NOV-2022 (Last updated, Version 26)
Name Archease_arch
Templates Q9V105 (ARCH_PYRAB); O59205 (ARCH_PYRHO): [Recover all]

Propagated annotation [?]

Identifier, protein and gene names [?]

Protein name
RecName: Full=Protein archease;

Comments [?]

Function Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently.
Similarity Belongs to the archease family.

Keywords [?]

Gene Ontology [?]

GO:0005509; Molecular function: calcium ion binding.
GO:0006388; Biological process: tRNA splicing, via endonucleolytic cleavage and ligation.

Cross-references [?]

Pfam PF01951; Archease; 1;

Features [?]

From: ARCH_PYRHO (O59205)
Key     From     To       Description   Tag   Condition   FTGroup
BINDING     12     12       /ligand="Ca(2+)" /ligand_id="ChEBI:CHEBI:29108     D  
BINDING     141     141       /ligand="Ca(2+)" /ligand_id="ChEBI:CHEBI:29108     D  
BINDING     Cter     Cter       /ligand="Ca(2+)" /ligand_id="ChEBI:CHEBI:29108     [ILVT]  

Additional information [?]

Size range 124-147 amino acids
Related rules None
Fusion None