HAMAP rule MF_01222
General rule information
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Accession | MF_01222 |
Dates | 2-SEP-2002 (Created)
19-NOV-2022 (Last updated, Version 26) |
Name | Archease_arch |
Scope(s) |
Bacteria Archaea |
Template(s) | Q9V105 (ARCH_PYRAB); O59205 (ARCH_PYRHO); [ Recover all ] |
Triggered by |
HAMAP; MF_01222 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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Identifier | ARCH |
Protein name | RecName: Full=Protein archease; |
Comments
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FUNCTION | Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently. |
SIMILARITY | Belongs to the archease family. |
Keywords
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Gene Ontology
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GO:0005509; Molecular function:calcium ion binding |
GO:0006388; Biological process:tRNA splicing, via endonucleolytic cleavage and ligation |
Cross-references
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Pfam | PF01951; Archease; 1; |
Features
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From: ARCH_PYRHO (O59205) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
BINDING | 12 | 12 | /ligand="Ca(2+)" /ligand_id="ChEBI:CHEBI:29108" |
D | ||||||||
BINDING | 141 | 141 | /ligand="Ca(2+)" /ligand_id="ChEBI:CHEBI:29108" |
D | ||||||||
BINDING | Cter | Cter | /ligand="Ca(2+)" /ligand_id="ChEBI:CHEBI:29108" |
[ILVT] |
Additional information
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Size range | 124-147 amino acids |
Related rules |
None |
Fusion | Nter: None Cter: None |