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Annotation rule MF_01242
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General rule information [?]

Accession MF_01242
Dates 23-MAY-2003 (Created)
19-NOV-2019 (Last updated, Version 18)
Name Aliphatic_amidase
Scope
Bacteria
Templates Q9L543 (AMIE_BACSP); Q9RQ17 (AMIE_GEOSE); O25067 (AMIE_HELPY); P11436 (AMIE_PSEAE); Q01360 (AMIE_RHOER): [Recover all]
Triggered by

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
AMIE
Protein name
RecName: Full=Aliphatic amidase;
EC 3.5.1.4;
AltName: Full=Acylamide amidohydrolase;
Gene name
amiE

Comments [?]

Function Catalyzes the hydrolysis of short-chain aliphatic amides to their corresponding organic acids with release of ammonia.
Also exhibits in vitro acyl transferase activity, transferring the acyl moiety of short-chain amides to hydroxylamine to form hydroxamates.
Catalytic activity RHEA:12020: a monocarboxylic acid amide + H2O = a monocarboxylate + NH4(+)
EC 3.5.1.4
Similarity Belongs to the carbon-nitrogen hydrolase superfamily. Aliphatic amidase family.

Keywords [?]

Hydrolase

Gene Ontology [?]

GO:0004040; Molecular function: amidase activity.

Cross-references [?]

Pfam PF00795; CN_hydrolase; 1;
PROSITE PS50263; CN_HYDROLASE; 1; trigger=PRU00054;

Features [?]

From: AMIE_PSEAE (P11436)
Key     From     To       Description   Tag   Condition   FTGroup
ACT_SITE     59     59       Proton acceptor     E  
ACT_SITE     134     134       Proton donor     K  
ACT_SITE     166     166       Nucleophile     C  

Additional information [?]

Size range 339-348 amino acids
Related rules MF_01243 (AMIF)
Fusion None


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