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Annotation rule MF_01242 |
Accession | MF_01242 |
Dates | 23-MAY-2003 (Created) 19-NOV-2019 (Last updated, Version 18) |
Name | Aliphatic_amidase |
Scope | Bacteria |
Templates | Q9L543 (AMIE_BACSP); Q9RQ17 (AMIE_GEOSE); O25067 (AMIE_HELPY); P11436 (AMIE_PSEAE); Q01360 (AMIE_RHOER): [Recover all] |
Triggered by |
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Protein name |
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Gene name |
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Function | Catalyzes the hydrolysis of short-chain aliphatic amides to their corresponding organic acids with release of ammonia. |
Also exhibits in vitro acyl transferase activity, transferring the acyl moiety of short-chain amides to hydroxylamine to form hydroxamates. | |
Catalytic activity | RHEA:12020: a monocarboxylic acid amide + H2O = a monocarboxylate + NH4(+)
EC 3.5.1.4 |
Similarity | Belongs to the carbon-nitrogen hydrolase superfamily. Aliphatic amidase family. |
From: AMIE_PSEAE (P11436) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
ACT_SITE | 59 | 59 | Proton acceptor | E | ||||||||
ACT_SITE | 134 | 134 | Proton donor | K | ||||||||
ACT_SITE | 166 | 166 | Nucleophile | C |
Size range | 339-348 amino acids |
Related rules | MF_01243 (AMIF) |
Fusion | None |