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HAMAP rule MF_01243

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General rule information [?]

Accession MF_01243
Dates 23-MAY-2003 (Created)
19-NOV-2019 (Last updated, Version 20)
Name Formamidase
Scope
Bacteria
Template O25836 (AMIF_HELPY)

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
AMIF
Protein name
RecName: Full=Formamidase;
EC 3.5.1.49;
AltName: Full=Formamide amidohydrolase;
Gene name
amiF

Comments [?]

Function Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide.
Catalytic activity RHEA:21948: formamide + H2O = formate + NH4(+)
EC 3.5.1.49
Similarity Belongs to the carbon-nitrogen hydrolase superfamily. Aliphatic amidase family.

Keywords [?]


Gene Ontology [?]

GO:0004328; Molecular function: formamidase activity.

Cross-references [?]

Pfam PF00795; CN_hydrolase; 1;
PROSITE PS50263; CN_HYDROLASE; 1; trigger=PRU00054;

Features [?]

From: AMIF_HELPY (O25836)
Key     From     To       Description   Tag   Condition   FTGroup
ACT_SITE     60     60       Proton acceptor     E  
ACT_SITE     133     133       Proton donor     K  
ACT_SITE     166     166       Nucleophile     C  

Additional information [?]

Size range 332-338 amino acids
Related rules MF_01242 (AMIE)
Fusion None