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HAMAP rule MF_01243

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General rule information [?]

Accession MF_01243
Dates 23-MAY-2003 (Created)
19-NOV-2019 (Last updated, Version 20)
Name Formamidase
Scope(s) Bacteria
Template(s) O25836 (AMIF_HELPY); [ Recover all ]
Triggered by HAMAP; MF_01243 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier AMIF
Protein name RecName: Full=Formamidase;
AltName: Full=Formamide amidohydrolase;
Gene name Name=amiF;

Comments [?]

FUNCTIONIs an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide.
CATALYTIC ACTIVITY Reaction=formamide + H2O = formate + NH4(+); Xref=Rhea:RHEA:21948, ChEBI:CHEBI:15377, ChEBI:CHEBI:15740, ChEBI:CHEBI:16397, ChEBI:CHEBI:28938; EC=;
SIMILARITYBelongs to the carbon-nitrogen hydrolase superfamily. Aliphatic amidase family.

Keywords [?]

Gene Ontology [?]

GO:0004328; Molecular function:formamidase activity

Cross-references [?]

Pfam PF00795; CN_hydrolase; 1;

Features [?]

From: AMIF_HELPY (O25836)
Key From To Description Tag Condition FTGroup
ACT_SITE 60 60 /note="Proton acceptor" E
ACT_SITE 133 133 /note="Proton donor" K
ACT_SITE 166 166 /note="Nucleophile" C

Additional information [?]

Size range 332-338 amino acids
Related rules MF_01242
Fusion Nter: None Cter: None

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