HAMAP rule MF_01243
General rule information
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| Accession | MF_01243 |
| Dates | 23-MAY-2003 (Created)
19-NOV-2019 (Last updated, Version 20) |
| Name | Formamidase |
| Scope(s) |
Bacteria |
| Template(s) | O25836 (AMIF_HELPY); [ Recover all ] |
| Triggered by |
HAMAP; MF_01243 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | AMIF |
| Protein name | RecName: Full=Formamidase; EC=3.5.1.49; AltName: Full=Formamide amidohydrolase; |
| Gene name | Name=amiF; |
Comments
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| FUNCTION | Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide. |
| CATALYTIC ACTIVITY | Reaction=formamide + H2O = formate + NH4(+); Xref=Rhea:RHEA:21948, ChEBI:CHEBI:15377, ChEBI:CHEBI:15740, ChEBI:CHEBI:16397, ChEBI:CHEBI:28938; EC=3.5.1.49; |
| SIMILARITY | Belongs to the carbon-nitrogen hydrolase superfamily. Aliphatic amidase family. |
Keywords
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Gene Ontology
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| GO:0004328; Molecular function:formamidase activity |
Cross-references
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Features
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| From: AMIF_HELPY (O25836) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| ACT_SITE | 60 | 60 | /note="Proton acceptor" | E | ||||||||
| ACT_SITE | 133 | 133 | /note="Proton donor" | K | ||||||||
| ACT_SITE | 166 | 166 | /note="Nucleophile" | C | ||||||||
Additional information
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| Size range | 332-338 amino acids |
| Related rules |
MF_01242 |
| Fusion | Nter: None Cter: None |