HAMAP logo

HAMAP rule MF_01246

Send feedback

General rule information [?]

Accession MF_01246
Dates 19-JUN-2003 (Created)
19-NOV-2022 (Last updated, Version 28)
Name COD
Scope(s) Bacteria
Template(s) P37794 (CHBG_ECOLI); P59745 (YDJC_ENTFA); [ Recover all ]
Triggered by HAMAP; MF_01246 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

case <OC:Enterobacterales>
Identifier CHBG
Protein name RecName: Full=Chitooligosaccharide deacetylase;
AltName: Full=Chitin disaccharide deacetylase;
AltName: Full=Chitobiose deacetylase;
AltName: Full=Chitobiose-6P deacetylase;
AltName: Full=Chitotriose deacetylase;
AltName: Full=Chitotriose-6P deacetylase;
Gene name Name=chbG;
Identifier YDJC
Protein name RecName: Full=Carbohydrate deacetylase;
end case

Comments [?]

case <OC:Enterobacterales>
FUNCTIONInvolved in the degradation of chitin. ChbG is essential for growth on the acetylated chitooligosaccharides chitobiose and chitotriose but is dispensable for growth on cellobiose and chitosan dimer, the deacetylated form of chitobiose. Deacetylation of chitobiose-6-P and chitotriose-6-P is necessary for both the activation of the chb promoter by the regulatory protein ChbR and the hydrolysis of phosphorylated beta-glucosides by the phospho-beta-glucosidase ChbF. Catalyzes the removal of only one acetyl group from chitobiose-6-P to yield monoacetylchitobiose-6-P, the inducer of ChbR and the substrate of ChbF.
CATALYTIC ACTIVITY Reaction=H2O + N,N'-diacetylchitobiose = acetate + N-acetyl-beta-D- glucosaminyl-(1->4)-D-glucosamine; Xref=Rhea:RHEA:27469, ChEBI:CHEBI:15377, ChEBI:CHEBI:28681, ChEBI:CHEBI:30089, ChEBI:CHEBI:59910; EC=;
CATALYTIC ACTIVITY Reaction=diacetylchitobiose-6'-phosphate + H2O = acetate + N'- monoacetylchitobiose-6'-phosphate; Xref=Rhea:RHEA:35083, ChEBI:CHEBI:15377, ChEBI:CHEBI:30089, ChEBI:CHEBI:64883, ChEBI:CHEBI:71315;
COFACTOR Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
PATHWAYGlycan degradation; chitin degradation.
SIMILARITYBelongs to the YdjC deacetylase family. ChbG subfamily.
FUNCTIONProbably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides.
COFACTOR Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
SIMILARITYBelongs to the YdjC deacetylase family.
end case

Keywords [?]

Gene Ontology [?]

case <OCellular component:Enterobacterales>
GO:0036311; Molecular function:chitin disaccharide deacetylase activity
GO:0052777; Biological process:diacetylchitobiose catabolic process
GO:0005737; Cellular component:cytoplasm
GO:0000272; Biological process:polysaccharide catabolic process
end case
GO:0016811; Molecular function:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides

Cross-references [?]

Pfam PF04794; YdjC; 1;

Features [?]

From: CHBG_ECOLI (P37794)
Key From To Description Tag Condition FTGroup
BINDING 61 61 /ligand="Mg(2+)"
BINDING 125 125 /ligand="Mg(2+)"

Additional information [?]

Size range 230-262 amino acids
Related rules None
Fusion Nter: None Cter: None

View rule in raw text format (no links)