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HAMAP rule MF_01251

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General rule information [?]

Accession MF_01251
Dates 6-MAY-2004 (Created)
1-JUN-2023 (Last updated, Version 30)
Name UPF0313
Template None

Propagated annotation [?]

Identifier, protein and gene names [?]

case <OC:Escherichia> or <OC:Shigella> or <OC:Salmonella>
Protein name
RecName: Full=UPF0313 protein YgiQ;
Gene name
Protein name
RecName: Full=UPF0313 protein ;
end case

Comments [?]

case <FTGroup:1>
Cofactor [4Fe-4S] cluster
Note: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
end case
Similarity Belongs to the UPF0313 family.

Keywords [?]

case <FTGroup:1>
end case

Gene Ontology [?]

case <FTGroup:1>
GO:0005506; Molecular function: iron ion binding.
end case

Cross-references [?]

Pfam PF04055; Radical_SAM; 1;
NCBIfam TIGR03904; SAM_YgiQ; 1;

Features [?]

From: YGIQ_ECOLI (Q46861)
Key     From     To       Description   Tag   Condition   FTGroup
BINDING     386     386       /ligand="[4Fe-4S] cluster" /ligand_id="ChEBI:CHEBI:49883" /ligand_note="4Fe-4S-S-AdoMet     C   1
BINDING     390     390       /ligand="[4Fe-4S] cluster" /ligand_id="ChEBI:CHEBI:49883" /ligand_note="4Fe-4S-S-AdoMet     C   1
BINDING     393     393       /ligand="[4Fe-4S] cluster" /ligand_id="ChEBI:CHEBI:49883" /ligand_note="4Fe-4S-S-AdoMet     C   1

Additional information [?]

Size range 550-830 amino acids
Related rules None
Fusion Nter: <Unknown>; Cter: None
Comments Proteins of this UPF may catalyze a radical-mediated reaction via the reductive cleavage of S-adenosylmethionine (SAM) through a peculiar Fe-S center. Sequence from YERPE is probably a pseudogene because it is frameshifted, but it has been rebuilt in this family. Unknown N-terminal domain in METAC; sequence not included in alignment.