HAMAP rule MF_01251
General rule information
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| PURL | https://purl.expasy.org/hamap/rule/MF_01251 |
| Accession | MF_01251 |
| Dates | 28-FEB-2005 (Created)
01-JUN-2023 (Last updated, Version 29) |
| Name | UPF0313 |
| Scope(s) |
Bacteria Archaea |
| Template(s) | None |
| Triggered by |
HAMAP; MF_01251 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| case <OC:Escherichia> or <OC:Shigella> or <OC:Salmonella> | |
| Identifier | YGIQ |
| Protein name | RecName: Full=UPF0313 protein YgiQ; |
| Gene name | Name=ygiQ; |
| else | |
| Identifier | Ynnn |
| Protein name | RecName: Full=UPF0313 protein |
| end case | |
Comments
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| case <FTGroup:1> | |
| COFACTOR | Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883; Note=Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.; |
| end case | |
| SIMILARITY | Belongs to the UPF0313 family. |
Keywords
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| case <FTGroup:1> | |
| 4Fe-4S | |
| Iron | |
| Iron-sulfur | |
| Metal-binding | |
| S-adenosyl-L-methionine | |
| end case | |
Gene Ontology
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| case <FTGroup:1> | |
| GO:0005506; Molecular function:iron ion binding | |
| end case | |
Cross-references
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Features
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| From: YGIQ_ECOLI (Q46861) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| BINDING | 386 | 386 | /ligand="[4Fe-4S] cluster" /ligand_id="ChEBI:CHEBI:49883" /ligand_note="4Fe-4S-S-AdoMet" |
C | 1 | |||||||
| BINDING | 390 | 390 | /ligand="[4Fe-4S] cluster" /ligand_id="ChEBI:CHEBI:49883" /ligand_note="4Fe-4S-S-AdoMet" |
C | 1 | |||||||
| BINDING | 393 | 393 | /ligand="[4Fe-4S] cluster" /ligand_id="ChEBI:CHEBI:49883" /ligand_note="4Fe-4S-S-AdoMet" |
C | 1 | |||||||
Additional information
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| Size range | 550-830 amino acids |
| Related rules |
None |
| Fusion | Nter: <Unknown> Cter: None |
| Comments | Proteins of this UPF may catalyze a radical-mediated reaction via the reductive cleavage of S-adenosylmethionine (SAM) through a peculiar Fe-S center. Sequence from YERPE is probably a pseudogene because it is frameshifted, but it has been rebuilt in this family. Unknown N-terminal domain in METAC; sequence not included in alignment. |