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Annotation rule MF_01254
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General rule information [?]

Accession MF_01254
Dates 16-DEC-2004 (Created)
19-NOV-2019 (Last updated, Version 24)
Name Fucose_iso
Scope
Bacteria
Template P69922 (FUCI_ECOLI)
Triggered by

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
FUCI
Protein name
RecName: Full=L-fucose isomerase;
Short=FucIase;
EC 5.3.1.25;
AltName: Full=6-deoxy-L-galactose isomerase;
Gene name
fucI

Comments [?]

Function Converts the aldose L-fucose into the corresponding ketose L-fuculose.
Catalytic activity RHEA:17233: L-fucose = L-fuculose
EC 5.3.1.25
Cofactor Mn(2+)
Pathway Carbohydrate degradation; L-fucose degradation; L-lactaldehyde and glycerone phosphate from L-fucose: step 1/3.
case <OC:Enterobacterales>
Subunit Homohexamer.
end case
Subcellular location Cytoplasm.
Similarity Belongs to the L-fucose isomerase family.

Keywords [?]

Cytoplasm
Carbohydrate metabolism
Fucose metabolism
Isomerase
case <FT:3> and <FT:4> and <FT:5>
Manganese
Metal-binding
end case

Gene Ontology [?]

GO:0008736; Molecular function: L-fucose isomerase activity.
case <FT:3> and <FT:4> and <FT:5>
GO:0030145; Molecular function: manganese ion binding.
end case
GO:0042355; Biological process: L-fucose catabolic process.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

Pfam PF02952; Fucose_iso_C; 1;
TIGRFAMs TIGR01089; FucI; 1;

Features [?]

From: FUCI_ECOLI (P69922)
Key     From     To       Description   Tag   Condition   FTGroup
ACT_SITE     337     337       Proton acceptor     E  
ACT_SITE     361     361       Proton acceptor     D  
METAL     337     337       Manganese     E  
METAL     361     361       Manganese     D  
METAL     528     528       Manganese     H  

Additional information [?]

Size range 560-620 amino acids
Related rules None
Fusion None


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