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HAMAP rule MF_01254

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General rule information [?]

Accession MF_01254
Dates 16-DEC-2004 (Created)
1-JUN-2023 (Last updated, Version 27)
Name Fucose_iso
Scope(s) Bacteria
Template(s) P69922 (FUCI_ECOLI); [ Recover all ]
Triggered by HAMAP; MF_01254 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier FUCI
Protein name RecName: Full=L-fucose isomerase;
AltName: Full=6-deoxy-L-galactose isomerase;
Gene name Name=fucI;

Comments [?]

FUNCTIONConverts the aldose L-fucose into the corresponding ketose L- fuculose.
CATALYTIC ACTIVITY Reaction=L-fucose = L-fuculose; Xref=Rhea:RHEA:17233, ChEBI:CHEBI:2181, ChEBI:CHEBI:17617; EC=;
COFACTOR Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
PATHWAYCarbohydrate degradation; L-fucose degradation; L-lactaldehyde and glycerone phosphate from L-fucose: step 1/3.
case <OC:Enterobacterales>
end case
SIMILARITYBelongs to the L-fucose isomerase family.

Keywords [?]

Gene Ontology [?]

GO:0008736; Molecular function:L-fucose isomerase activity
case <FT:3> and <FT:4> and <FT:5>
GO:0030145; Molecular function:manganese ion binding
end case
GO:0042355; Biological process:L-fucose catabolic process
GO:0005737; Cellular component:cytoplasm

Cross-references [?]

Pfam PF02952; Fucose_iso_C; 1;
NCBIfam TIGR01089; FucI; 1;

Features [?]

From: FUCI_ECOLI (P69922)
Key From To Description Tag Condition FTGroup
ACT_SITE 337 337 /note="Proton acceptor" E
ACT_SITE 361 361 /note="Proton acceptor" D
BINDING 337 337 /ligand="Mn(2+)"
BINDING 361 361 /ligand="Mn(2+)"
BINDING 528 528 /ligand="Mn(2+)"

Additional information [?]

Size range 560-620 amino acids
Related rules None
Fusion Nter: None Cter: None

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