HAMAP rule MF_01255
General rule information
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| Accession | MF_01255 |
| Dates | 13-JAN-2005 (Created)
19-NOV-2019 (Last updated, Version 19) |
| Name | Ectoine_synth |
| Scope(s) |
Bacteria |
| Template(s) | O52251 (ECTC_HALED); O06061 (ECTC_MARHA); Q9AP33 (ECTC_SPOPA); [ Recover all ] |
| Triggered by |
HAMAP; MF_01255 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | ECTC |
| Protein name | RecName: Full=L-ectoine synthase; EC=4.2.1.108; AltName: Full=N-acetyldiaminobutyrate dehydratase; |
| Gene name | Name=ectC; |
Comments
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| FUNCTION | Catalyzes the circularization of gamma-N-acetyl-alpha,gamma- diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4- pyrimidine carboxylic acid), which is an excellent osmoprotectant. |
| CATALYTIC ACTIVITY | Reaction=(2S)-4-acetamido-2-aminobutanoate = H2O + L-ectoine; Xref=Rhea:RHEA:17281, ChEBI:CHEBI:15377, ChEBI:CHEBI:58515, ChEBI:CHEBI:58929; EC=4.2.1.108; |
| PATHWAY | Amine and polyamine biosynthesis; ectoine biosynthesis; L- ectoine from L-aspartate 4-semialdehyde: step 3/3. |
| SIMILARITY | Belongs to the ectoine synthase family. |
Keywords
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Gene Ontology
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| GO:0016836; Molecular function:hydro-lyase activity |
| GO:0019491; Biological process:ectoine biosynthetic process |
Cross-references
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| Pfam | PF06339; Ectoine_synth; 1; |
Features
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Additional information
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| Size range | 128-138 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |
| Comments | This protein is mainly found in halophilic bacteria, which synthesize ectoine as a good osmoprotectant. |