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Annotation rule MF_01255
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General rule information [?]

Accession MF_01255
Dates 13-JAN-2005 (Created)
19-NOV-2019 (Last updated, Version 19)
Name Ectoine_synth
Scope
Bacteria
Templates O52251 (ECTC_HALED); O06061 (ECTC_MARHA); Q9AP33 (ECTC_SPOPA): [Recover all]

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
ECTC
Protein name
RecName: Full=L-ectoine synthase;
EC 4.2.1.108;
AltName: Full=N-acetyldiaminobutyrate dehydratase;
Gene name
ectC

Comments [?]

Function Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant.
Catalytic activity RHEA:17281: (2S)-4-acetamido-2-aminobutanoate = H2O + L-ectoine
EC 4.2.1.108
Pathway Amine and polyamine biosynthesis; ectoine biosynthesis; L-ectoine from L-aspartate 4-semialdehyde: step 3/3.
Similarity Belongs to the ectoine synthase family.

Keywords [?]


Gene Ontology [?]

GO:0016836; Molecular function: hydro-lyase activity.
GO:0019491; Biological process: ectoine biosynthetic process.

Cross-references [?]

Pfam PF06339; Ectoine_synth; 1;

Additional information [?]

Size range 128-138 amino acids
Related rules None
Fusion None
Comments This protein is mainly found in halophilic bacteria, which synthesize ectoine as a good osmoprotectant.