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Annotation rule MF_01255 |
Accession | MF_01255 |
Dates | 13-JAN-2005 (Created) 19-NOV-2019 (Last updated, Version 19) |
Name | Ectoine_synth |
Scope | Bacteria |
Templates | O52251 (ECTC_HALED); O06061 (ECTC_MARHA); Q9AP33 (ECTC_SPOPA): [Recover all] |
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Function | Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant. |
Catalytic activity | RHEA:17281: (2S)-4-acetamido-2-aminobutanoate = H2O + L-ectoine
EC 4.2.1.108 |
Pathway | Amine and polyamine biosynthesis; ectoine biosynthesis; L-ectoine from L-aspartate 4-semialdehyde: step 3/3. |
Similarity | Belongs to the ectoine synthase family. |
Pfam | PF06339; Ectoine_synth; 1; |
Size range | 128-138 amino acids |
Related rules | None |
Fusion | None |
Comments | This protein is mainly found in halophilic bacteria, which synthesize ectoine as a good osmoprotectant. |