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HAMAP rule MF_01255

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General rule information [?]

Accession MF_01255
Dates 13-JAN-2005 (Created)
19-NOV-2019 (Last updated, Version 19)
Name Ectoine_synth
Scope(s) Bacteria
Template(s) O52251 (ECTC_HALED); O06061 (ECTC_MARHA); Q9AP33 (ECTC_SPOPA); [ Recover all ]
Triggered by HAMAP; MF_01255 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier ECTC
Protein name RecName: Full=L-ectoine synthase;
AltName: Full=N-acetyldiaminobutyrate dehydratase;
Gene name Name=ectC;

Comments [?]

FUNCTIONCatalyzes the circularization of gamma-N-acetyl-alpha,gamma- diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4- pyrimidine carboxylic acid), which is an excellent osmoprotectant.
CATALYTIC ACTIVITY Reaction=(2S)-4-acetamido-2-aminobutanoate = H2O + L-ectoine; Xref=Rhea:RHEA:17281, ChEBI:CHEBI:15377, ChEBI:CHEBI:58515, ChEBI:CHEBI:58929; EC=;
PATHWAYAmine and polyamine biosynthesis; ectoine biosynthesis; L- ectoine from L-aspartate 4-semialdehyde: step 3/3.
SIMILARITYBelongs to the ectoine synthase family.

Keywords [?]

Gene Ontology [?]

GO:0016836; Molecular function:hydro-lyase activity
GO:0019491; Biological process:ectoine biosynthetic process

Cross-references [?]

Pfam PF06339; Ectoine_synth; 1;

Features [?]

Additional information [?]

Size range 128-138 amino acids
Related rules None
Fusion Nter: None Cter: None
Comments This protein is mainly found in halophilic bacteria, which synthesize ectoine as a good osmoprotectant.

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