 |
|
| Annotation rule MF_01255 |
General rule information
[?]
| Accession | MF_01255 |
| Dates | 13-JAN-2005 (Created) 19-NOV-2019 (Last updated, Version 19) |
| Name | Ectoine_synth |
| Scope | Bacteria |
| Templates | O52251 (ECTC_HALED); O06061 (ECTC_MARHA); Q9AP33 (ECTC_SPOPA): [Recover all] |
| Triggered by |
Propagated annotation
[?]
Identifier, protein and gene names
[?]
| Identifier |
|
| Protein name |
|
||||||||||||
| Gene name |
|
Comments
[?]
| Function | Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant. |
| Catalytic activity | RHEA:17281: (2S)-4-acetamido-2-aminobutanoate = H2O + L-ectoine
EC 4.2.1.108 |
| Pathway | Amine and polyamine biosynthesis; ectoine biosynthesis; L-ectoine from L-aspartate 4-semialdehyde: step 3/3. |
| Similarity | Belongs to the ectoine synthase family. |
Keywords
[?]
Gene Ontology
[?]
GO:0016836; Molecular function: hydro-lyase activity.
GO:0019491; Biological process: ectoine biosynthetic process.
GO:0019491; Biological process: ectoine biosynthetic process.
Cross-references
[?]
| Pfam | PF06339; Ectoine_synth; 1; |
Additional information
[?]
| Size range | 128-138 amino acids |
| Related rules | None |
| Fusion | None |
| Comments | This protein is mainly found in halophilic bacteria, which synthesize ectoine as a good osmoprotectant. |