HAMAP logo

HAMAP rule MF_01270

Send feedback

General rule information [?]

Accession MF_01270
Dates 31-AUG-2006 (Created)
19-NOV-2022 (Last updated, Version 18)
Name AnhMurNAc_kinase
Template P77570 (ANMK_ECOLI)

Propagated annotation [?]

Identifier, protein and gene names [?]

Protein name
RecName: Full=Anhydro-N-acetylmuramic acid kinase;
AltName: Full=AnhMurNAc kinase;
Gene name

Comments [?]

Function Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
Catalytic activity RHEA:24952: 1,6-anhydro-N-acetyl-beta-muramate + ATP + H2O = ADP + H(+) + N-acetyl-D-muramate 6-phosphate
Pathway Amino-sugar metabolism; 1,6-anhydro-N-acetylmuramate degradation.
Cell wall biogenesis; peptidoglycan recycling.
Similarity Belongs to the anhydro-N-acetylmuramic acid kinase family.

Keywords [?]

Gene Ontology [?]

GO:0005524; Molecular function: ATP binding.
GO:0016773; Molecular function: phosphotransferase activity, alcohol group as acceptor.
GO:0006040; Biological process: amino sugar metabolic process.
GO:0009254; Biological process: peptidoglycan turnover.

Cross-references [?]

Pfam PF03702; UPF0075; 1;

Features [?]

From: ANMK_ECOLI (P77570)
Key     From     To       Description   Tag   Condition   FTGroup
BINDING     12     19       /ligand="ATP" /ligand_id="ChEBI:CHEBI:30616        

Additional information [?]

Size range 355-436 amino acids
Related rules None
Fusion None