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HAMAP rule MF_01270

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General rule information [?]

Accession MF_01270
Dates 31-AUG-2006 (Created)
19-NOV-2022 (Last updated, Version 18)
Name AnhMurNAc_kinase
Scope(s) Bacteria
Template(s) P77570 (ANMK_ECOLI); [ Recover all ]
Triggered by HAMAP; MF_01270 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier ANMK
Protein name RecName: Full=Anhydro-N-acetylmuramic acid kinase;
AltName: Full=AnhMurNAc kinase;
Gene name Name=anmK;

Comments [?]

FUNCTIONCatalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
CATALYTIC ACTIVITY Reaction=1,6-anhydro-N-acetyl-beta-muramate + ATP + H2O = ADP + H(+) + N-acetyl-D-muramate 6-phosphate; Xref=Rhea:RHEA:24952, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:58690, ChEBI:CHEBI:58722, ChEBI:CHEBI:456216; EC=;
PATHWAYAmino-sugar metabolism; 1,6-anhydro-N-acetylmuramate degradation.
PATHWAYCell wall biogenesis; peptidoglycan recycling.
SIMILARITYBelongs to the anhydro-N-acetylmuramic acid kinase family.

Keywords [?]

Gene Ontology [?]

GO:0005524; Molecular function:ATP binding
GO:0016773; Molecular function:phosphotransferase activity, alcohol group as acceptor
GO:0006040; Biological process:amino sugar metabolic process
GO:0009254; Biological process:peptidoglycan turnover

Cross-references [?]

Pfam PF03702; UPF0075; 1;

Features [?]

From: ANMK_ECOLI (P77570)
Key From To Description Tag Condition FTGroup
BINDING 12 19 /ligand="ATP"

Additional information [?]

Size range 355-436 amino acids
Related rules None
Fusion Nter: None Cter: None

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