HAMAP rule MF_01270
General rule information
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| Accession | MF_01270 |
| Dates | 31-AUG-2006 (Created) 19-NOV-2022 (Last updated, Version 18) |
| Name | AnhMurNAc_kinase |
| Scope | Bacteria |
| Template | P77570 (ANMK_ECOLI) |
| Triggered by |
Propagated annotation
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Identifier, protein and gene names
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| Identifier |
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| Protein name |
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| Gene name |
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Comments
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| Function | Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling. |
| Catalytic activity | RHEA:24952: 1,6-anhydro-N-acetyl-beta-muramate + ATP + H2O = ADP + H(+) + N-acetyl-D-muramate 6-phosphate
EC 2.7.1.170 |
| Pathway | Amino-sugar metabolism; 1,6-anhydro-N-acetylmuramate degradation. |
| Cell wall biogenesis; peptidoglycan recycling. | |
| Similarity | Belongs to the anhydro-N-acetylmuramic acid kinase family. |
Keywords
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Gene Ontology
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GO:0005524; Molecular function: ATP binding.
GO:0016773; Molecular function: phosphotransferase activity, alcohol group as acceptor.
GO:0006040; Biological process: amino sugar metabolic process.
GO:0009254; Biological process: peptidoglycan turnover.
GO:0016773; Molecular function: phosphotransferase activity, alcohol group as acceptor.
GO:0006040; Biological process: amino sugar metabolic process.
GO:0009254; Biological process: peptidoglycan turnover.
Cross-references
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| Pfam | PF03702; UPF0075; 1; |
Features
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| From: ANMK_ECOLI (P77570) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| BINDING | 12 | 19 | /ligand="ATP" /ligand_id="ChEBI:CHEBI:30616 | |||||||||
Additional information
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| Size range | 355-436 amino acids |
| Related rules | None |
| Fusion | None |