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HAMAP rule MF_01296

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General rule information [?]

Accession MF_01296
Dates 30-MAR-2009 (Created)
1-JUN-2023 (Last updated, Version 11)
Name Tagatose_aldol_GatZ
Scope(s) Bacteria
Template(s) P0C8J8 (GATZ_ECOLI); P0C8J9 (GATZ_ECOLX); Q8VS12 (GATZ_KLEOX); [ Recover all ]
Triggered by HAMAP; MF_01296 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier GATZ
Protein name RecName: Full=D-tagatose-1,6-bisphosphate aldolase subunit GatZ;
Gene name Name=gatZ;

Comments [?]

FUNCTIONComponent of the tagatose-1,6-bisphosphate aldolase GatYZ that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of GatY. When expressed alone, GatZ does not show any aldolase activity. Is involved in the catabolism of galactitol.
PATHWAYCarbohydrate metabolism; D-tagatose 6-phosphate degradation; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-tagatose 6- phosphate: step 2/2.
SUBUNITForms a complex with GatY.
SIMILARITYBelongs to the GatZ/KbaZ family. GatZ subfamily.

Keywords [?]

Gene Ontology [?]

GO:0019404; Biological process:galactitol catabolic process

Cross-references [?]

Pfam PF08013; Tagatose_6_P_K; 1;
NCBIfam TIGR02810; AgaZ_gatZ; 1;

Features [?]

Additional information [?]

Size range 419-423 amino acids
Related rules MF_01295
Fusion Nter: None Cter: None
Comments Subunit GatY is described in MF_01294. In some enterobacteria, a second D-tagatose-1,6-bisphosphate aldolase is present: KbaYZ (MF_01293 and MF_01295).

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