HAMAP rule MF_01299
General rule information
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| Accession | MF_01299 |
| Dates | 20-JAN-2009 (Created) 26-JAN-2023 (Last updated, Version 16) |
| Name | OadC |
| Scope | Bacteria; Pseudomonadota |
| Template | Q9HUU1 (OADC_PSEAE) |
| Triggered by |
Propagated annotation
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Identifier, protein and gene names
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| Identifier |
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| Protein name |
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Comments
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| Function | Catalyzes the decarboxylation of oxaloacetate into pyruvate. Seems to play a role in maintaining cellular concentrations of bicarbonate and pyruvate. |
| Catalytic activity | RHEA:15641: H(+) + oxaloacetate = CO2 + pyruvate
EC 4.1.1.112 |
case <FT:1>
| Cofactor | Mg(2+) Note: Binds 1 Mg(2+) ion per subunit. |
end case
| Subunit | Homotetramer; dimer of dimers. |
| Similarity | Belongs to the isocitrate lyase family. Oxaloacetate decarboxylase subfamily. |
Keywords
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case <FT:1>
end case
Gene Ontology
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case <FT:1>
GO:0000287; Molecular function: magnesium ion binding.
end case
GO:0008948; Molecular function: oxaloacetate decarboxylase activity.
GO:0006107; Biological process: oxaloacetate metabolic process.
GO:0042866; Biological process: pyruvate biosynthetic process.
GO:0006107; Biological process: oxaloacetate metabolic process.
GO:0042866; Biological process: pyruvate biosynthetic process.
Features
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| From: OADC_PSEAE (Q9HUU1) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| BINDING | 88 | 88 | /ligand="Mg(2+)" /ligand_id="ChEBI:CHEBI:18420 | D | ||||||||
| BINDING | 50 | 50 | /ligand="substrate | S | ||||||||
| BINDING | 159 | 159 | /ligand="substrate | R | ||||||||
| BINDING | 235 | 235 | /ligand="substrate | H | ||||||||
Additional information
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| Size range | 287-302 amino acids |
| Related rules | None |
| Fusion | None |