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HAMAP rule MF_01299

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General rule information [?]

Accession MF_01299
Dates 20-JAN-2009 (Created)
26-JAN-2023 (Last updated, Version 16)
Name OadC
Bacteria; Pseudomonadota
Template Q9HUU1 (OADC_PSEAE)

Propagated annotation [?]

Identifier, protein and gene names [?]

Protein name
RecName: Full=Oxaloacetate decarboxylase;

Comments [?]

Function Catalyzes the decarboxylation of oxaloacetate into pyruvate. Seems to play a role in maintaining cellular concentrations of bicarbonate and pyruvate.
Catalytic activity RHEA:15641: H(+) + oxaloacetate = CO2 + pyruvate
case <FT:1>
Cofactor Mg(2+)
Note: Binds 1 Mg(2+) ion per subunit.
end case
Subunit Homotetramer; dimer of dimers.
Similarity Belongs to the isocitrate lyase family. Oxaloacetate decarboxylase subfamily.

Keywords [?]

case <FT:1>
end case

Gene Ontology [?]

case <FT:1>
GO:0000287; Molecular function: magnesium ion binding.
end case
GO:0008948; Molecular function: oxaloacetate decarboxylase activity.
GO:0006107; Biological process: oxaloacetate metabolic process.
GO:0042866; Biological process: pyruvate biosynthetic process.

Features [?]

Key     From     To       Description   Tag   Condition   FTGroup
BINDING     88     88       /ligand="Mg(2+)" /ligand_id="ChEBI:CHEBI:18420     D  
BINDING     50     50       /ligand="substrate     S  
BINDING     159     159       /ligand="substrate     R  
BINDING     235     235       /ligand="substrate     H  

Additional information [?]

Size range 287-302 amino acids
Related rules None
Fusion None