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HAMAP rule MF_01299

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General rule information [?]

Accession MF_01299
Dates 20-JAN-2009 (Created)
26-JAN-2023 (Last updated, Version 16)
Name OadC
Scope(s) Bacteria
Template(s) Q9HUU1 (OADC_PSEAE); [ Recover all ]
Triggered by HAMAP; MF_01299 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier OADC
Protein name RecName: Full=Oxaloacetate decarboxylase;

Comments [?]

FUNCTIONCatalyzes the decarboxylation of oxaloacetate into pyruvate. Seems to play a role in maintaining cellular concentrations of bicarbonate and pyruvate.
CATALYTIC ACTIVITY Reaction=H(+) + oxaloacetate = CO2 + pyruvate; Xref=Rhea:RHEA:15641, ChEBI:CHEBI:15361, ChEBI:CHEBI:15378, ChEBI:CHEBI:16452, ChEBI:CHEBI:16526; EC=;
case <FT:1>
COFACTOR Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Note=Binds 1 Mg(2+) ion per subunit.;
end case
SUBUNITHomotetramer; dimer of dimers.
SIMILARITYBelongs to the isocitrate lyase family. Oxaloacetate decarboxylase subfamily.

Keywords [?]

Gene Ontology [?]

case <FT:1>
GO:0000287; Molecular function:magnesium ion binding
end case
GO:0008948; Molecular function:oxaloacetate decarboxylase activity
GO:0006107; Biological process:oxaloacetate metabolic process
GO:0042866; Biological process:pyruvate biosynthetic process

Cross-references [?]

Features [?]

Key From To Description Tag Condition FTGroup
BINDING 88 88 /ligand="Mg(2+)"
BINDING 50 50 /ligand="substrate" S
BINDING 159 159 /ligand="substrate" R
BINDING 235 235 /ligand="substrate" H

Additional information [?]

Size range 287-302 amino acids
Related rules None
Fusion Nter: None Cter: None

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