HAMAP rule MF_01313

General rule information [?]

Accession	MF_01313
Dates	18-MAR-2003 (Created) 12-JAN-2021 (Last updated, Version 28)

Name

NorW

Scope

Bacteria; Aeromonas

Bacteria; Aliivibrio

Bacteria; Citrobacter

Bacteria; Escherichia

Bacteria; Enterobacter

Bacteria; Klebsiella

Bacteria; Pectobacterium

Bacteria; Salmonella

Bacteria; Serratia

Bacteria; Shigella

Bacteria; Vibrio

Template

P37596 (NORW_ECOLI)

Triggered by

HAMAP; MF_01313 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier

NORW

Protein name

RecName:		Full=Nitric oxide reductase FlRd-NAD(+) reductase;
		EC 1.18.1.-;
AltName:		Full=Flavorubredoxin reductase;
		Short=FlRd-reductase;
		Short=FlavoRb reductase;

Gene name

norW, flrR

Comments [?]

Function	One of at least two accessory proteins for anaerobic nitric oxide (NO) reductase. Reduces the rubredoxin moiety of NO reductase.
Catalytic activity	RHEA:42960: H(+) + NAD(+) + 2 reduced [nitric oxide reductase rubredoxin domain] = NADH + 2 oxidized [nitric oxide reductase rubredoxin domain]
Cofactor	FAD
Pathway	Nitrogen metabolism; nitric oxide reduction.
Subcellular location	Cytoplasm.
Similarity	Belongs to the FAD-dependent oxidoreductase family.

Keywords [?]

Cytoplasm
Oxidoreductase
Flavoprotein
FAD
NAD

Gene Ontology [?]

GO:0016731; Molecular function: oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

Pfam	PF00070; Pyr_redox; 1;
	PF07992; Pyr_redox_2; 1;
PRINTS	PR00368; FADPNR; 1;

Additional information [?]

Size range	377-388 amino acids
Related rules	None
Fusion	None
Comments	Restricted to lineages where there are norR and norV upstream.

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