HAMAP rule MF_01313
General rule information
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| PURL | https://purl.expasy.org/hamap/rule/MF_01313 |
| Accession | MF_01313 |
| Dates | 28-FEB-2005 (Created)
02-SEP-2024 (Last updated, Version 26) |
| Name | NorW |
| Scope(s) |
Bacteria Aeromonas Aliivibrio Citrobacter Escherichia Enterobacter Klebsiella Pectobacterium Salmonella Serratia Shigella Vibrio |
| Template(s) | P37596; [ Recover all ] |
| Triggered by |
HAMAP; MF_01313 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | NORW |
| Protein name | RecName: Full=Nitric oxide reductase FlRd-NAD(+) reductase; EC=1.18.1.-; AltName: Full=Flavorubredoxin reductase; Short=FlRd-reductase; Short=FlavoRb reductase; |
| Gene name | Name=norW; Synonyms=flrR; |
Comments
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| FUNCTION | One of at least two accessory proteins for anaerobic nitric oxide (NO) reductase. Reduces the rubredoxin moiety of NO reductase. |
| CATALYTIC ACTIVITY | Reaction=2 reduced [nitric oxide reductase rubredoxin domain] + NAD(+) + H(+) = 2 oxidized [nitric oxide reductase rubredoxin domain] + NADH; Xref=Rhea:RHEA:42960, Rhea:RHEA-COMP:10304, Rhea:RHEA- COMP:10305, ChEBI:CHEBI:15378, ChEBI:CHEBI:29033, ChEBI:CHEBI:29034, ChEBI:CHEBI:57540, ChEBI:CHEBI:57945; |
| COFACTOR | Name=FAD; Xref=ChEBI:CHEBI:57692; |
| PATHWAY | Nitrogen metabolism; nitric oxide reduction. |
| SUBCELLULAR LOCATION | Cytoplasm. |
| SIMILARITY | Belongs to the FAD-dependent oxidoreductase family. |
Keywords
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Gene Ontology
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| GO:0016731; Molecular function:oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor |
| GO:0005737; Cellular component:cytoplasm |
Cross-references
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Features
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Additional information
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| Size range | 377-388 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |
| Comments | Restricted to lineages where there are norR and norV upstream. |