HAMAP rule MF_01319
General rule information
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Accession | MF_01319 |
Dates | 27-AUG-2003 (Created) 15-FEB-2022 (Last updated, Version 30) |
Name | ResA |
Scope | Bacteria; Bacillaceae |
Template | P35160 (RESA_BACSU) |
Triggered by |
Propagated annotation
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Identifier, protein and gene names
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Identifier |
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Protein name |
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Gene name |
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Comments
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Function | Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c; following this reduction heme can be covalently attached. |
Pathway | Protein modification; cytochrome c assembly. |
Subcellular location | Cell membrane; Single-pass type II membrane protein. Note=The thioredoxin-like motif is exposed on the outside of the membrane. |
Similarity | Belongs to the thioredoxin family. ResA subfamily. |
Keywords
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case <FT:2>
end case
Gene Ontology
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GO:0015036; Molecular function: disulfide oxidoreductase activity.
GO:0017004; Biological process: cytochrome complex assembly.
GO:0005886; Cellular component: plasma membrane.
GO:0017004; Biological process: cytochrome complex assembly.
GO:0005886; Cellular component: plasma membrane.
Cross-references
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Pfam | PF00578; AhpC-TSA; 1; |
PROSITE | PS00194; THIOREDOXIN_1; 1; |
PS51352; THIOREDOXIN_2; 1; trigger=PRU00691; |
Features
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From: RESA_BACSU (P35160) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
TRANSMEM | 11 | 30 | Helical; Signal-anchor for type II membrane protein | |||||||||
DISULFID | 74 | 77 | Redox-active | C-x-P-C |
Additional information
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Size range | 173-192 amino acids |
Related rules | None |
Fusion | None |