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HAMAP rule MF_01319

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General rule information [?]

Accession MF_01319
Dates 27-AUG-2003 (Created)
15-FEB-2022 (Last updated, Version 30)
Name ResA
Scope(s) Bacteria
Bacillaceae
Template(s) P35160 (RESA_BACSU); [ Recover all ]
Triggered by HAMAP; MF_01319 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier RESA
Protein name RecName: Full=Thiol-disulfide oxidoreductase ResA;
Gene name Name=resA;

Comments [?]

FUNCTIONThiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c; following this reduction heme can be covalently attached.
PATHWAYProtein modification; cytochrome c assembly.
SUBCELLULAR LOCATIONCell membrane; Single-pass type II membrane protein. Note=The thioredoxin-like motif is exposed on the outside of the membrane.
SIMILARITYBelongs to the thioredoxin family. ResA subfamily.

Keywords [?]


Gene Ontology [?]

GO:0015036; Molecular function:disulfide oxidoreductase activity
GO:0017004; Biological process:cytochrome complex assembly
GO:0005886; Cellular component:plasma membrane

Cross-references [?]

Pfam PF00578; AhpC-TSA; 1;
PROSITE PS00194; THIOREDOXIN_1; 1;
PROSITE PS51352; THIOREDOXIN_2; 1;

Features [?]

From: RESA_BACSU (P35160)
Key From To Description Tag Condition FTGroup
TRANSMEM 11 30 /note="Helical; Signal-anchor for type II membrane protein"
DISULFID 74 77 /note="Redox-active" C-x-P-C

Additional information [?]

Size range 173-192 amino acids
Related rules None
Fusion Nter: None Cter: None



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