HAMAP rule MF_01319
General rule information
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Accession | MF_01319 |
Dates | 27-AUG-2003 (Created)
15-FEB-2022 (Last updated, Version 30) |
Name | ResA |
Scope(s) |
Bacteria Bacillaceae |
Template(s) | P35160 (RESA_BACSU); [ Recover all ] |
Triggered by |
HAMAP; MF_01319 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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Identifier | RESA |
Protein name | RecName: Full=Thiol-disulfide oxidoreductase ResA; |
Gene name | Name=resA; |
Comments
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FUNCTION | Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c; following this reduction heme can be covalently attached. |
PATHWAY | Protein modification; cytochrome c assembly. |
SUBCELLULAR LOCATION | Cell membrane; Single-pass type II membrane protein. Note=The thioredoxin-like motif is exposed on the outside of the membrane. |
SIMILARITY | Belongs to the thioredoxin family. ResA subfamily. |
Keywords
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Cell membrane | |
Cytochrome c-type biogenesis | |
case <FT:2> | |
Disulfide bond | |
end case | |
Membrane | |
Oxidoreductase | |
Redox-active center | |
Signal-anchor | |
Transmembrane | |
Transmembrane helix |
Gene Ontology
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GO:0015036; Molecular function:disulfide oxidoreductase activity |
GO:0017004; Biological process:cytochrome complex assembly |
GO:0005886; Cellular component:plasma membrane |
Cross-references
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Features
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From: RESA_BACSU (P35160) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
TRANSMEM | 11 | 30 | /note="Helical; Signal-anchor for type II membrane protein" | |||||||||
DISULFID | 74 | 77 | /note="Redox-active" | C-x-P-C |
Additional information
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Size range | 173-192 amino acids |
Related rules |
None |
Fusion | Nter: None Cter: None |