HAMAP rule MF_01325
General rule information
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| Accession | MF_01325 |
| Dates | 4-FEB-2004 (Created)
22-SEP-2023 (Last updated, Version 34) |
| Name | Ribosomal_uL3 |
| Scope(s) |
Bacteria Archaea Plastid |
| Template(s) | Q5SHN8 (RL3_THET8); P20279 (RL3_HALMA); Q9RXK2 (RL3_DEIRA); P60438 (RL3_ECOLI); [ Recover all ] |
| Triggered by |
case c? <OC:Bacteria> or <OG:Chloroplast>
HAMAP; MF_01325_B (Get profile general information and statistics) end case
case c? <OC:Archaea>
HAMAP; MF_01325_A (Get profile general information and statistics) end case
|
Propagated annotation
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Identifier, protein and gene names
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| case <OC:Bacteria> and not <OC:Cyanobacteriota> | |
| Identifier | RL3 |
| Protein name | RecName: Full=Large ribosomal subunit protein uL3; |
| Gene name | Name=rplC; |
| else case <OC:Cyanobacteriota> | |
| Identifier | RL3 |
| Protein name | RecName: Full=Large ribosomal subunit protein uL3; |
| Gene name | Name=rplC; Synonyms=rpl3; |
| else case <OC:Archaea> | |
| Identifier | RL3 |
| Protein name | RecName: Full=Large ribosomal subunit protein uL3; |
| Gene name | Name=rpl3; |
| else case <OG:Chloroplast> | |
| Identifier | RK3 |
| Protein name | RecName: Full=Large ribosomal subunit protein uL3c; |
| Gene name | Name=rpl3; |
| end case | |
Comments
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| FUNCTION | One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. |
| case <OC:Bacteria> | |
| SUBUNIT | Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19. |
| else case <OC:Archaea> | |
| SUBUNIT | Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L24e. |
| else case <OG:Chloroplast> | |
| SUBUNIT | Part of the 50S ribosomal subunit. |
| SUBCELLULAR LOCATION | Plastid, chloroplast. |
| end case | |
| case <OC:Pseudomonadota> and <FTTag:Methylation> | |
| PTM | Methylated by PrmB. |
| end case | |
| SIMILARITY | Belongs to the universal ribosomal protein uL3 family. |
Keywords
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| Ribonucleoprotein | |
| Ribosomal protein | |
| RNA-binding | |
| rRNA-binding | |
| case <FTTag:Methylation> | |
| Methylation | |
| end case | |
Gene Ontology
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| GO:0019843; Molecular function:rRNA binding | |
| GO:0006412; Biological process:translation | |
| case <OG:Chloroplast> | |
| GO:0009507; Cellular component:chloroplast | |
| end case | |
Cross-references
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| Pfam | PF00297; Ribosomal_L3; 1; |
| PROSITE | PS00474; RIBOSOMAL_L3; 1; |
| NCBIfam | TIGR03626; L3_arch; 1; |
| NCBIfam | TIGR03625; L3_bact; 1; |
Features
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| From: RL3_ECOLI (P60438) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| case <OC:Pseudomonadota> | ||||||||||||
| MOD_RES | 150 | 150 | /note="N5-methylglutamine" | Methylation | Q | |||||||
| end case | ||||||||||||
Additional information
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| Size range | 310-399 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |
| Comments | The Epsilonproteobacteria form a distinct sub-group within this family; they have been made atypical. |