HAMAP rule MF_01328
General rule information
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| Accession | MF_01328 |
| Dates | 29-MAR-2004 (Created)
1-JUN-2023 (Last updated, Version 33) |
| Name | Ribosomal_L4 |
| Scope(s) |
Bacteria Archaea Plastid |
| Template(s) | P60723 (RL4_ECOLI); Q9RXK1 (RL4_DEIRA); P12735 (RL4_HALMA); Q5SHN9 (RL4_THET8); [ Recover all ] |
| Triggered by |
case c? <OC:Bacteria> or <OG:Chloroplast>
HAMAP; MF_01328_B (Get profile general information and statistics) end case
case c? <OC:Archaea>
HAMAP; MF_01328_A (Get profile general information and statistics) end case
|
Propagated annotation
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Identifier, protein and gene names
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| case <OC:Bacteria> and not <OC:Cyanobacteriota> | |
| Identifier | RL4 |
| Protein name | RecName: Full=Large ribosomal subunit protein uL4; |
| Gene name | Name=rplD; |
| else case <OC:Cyanobacteriota> | |
| Identifier | RL4 |
| Protein name | RecName: Full=Large ribosomal subunit protein uL4; |
| Gene name | Name=rplD; Synonyms=rpl4; |
| else case <OC:Archaea> | |
| Identifier | RL4 |
| Protein name | RecName: Full=Large ribosomal subunit protein uL4; |
| Gene name | Name=rpl4; |
| else case <OG:Chloroplast> | |
| Identifier | RK4 |
| Protein name | RecName: Full=Large ribosomal subunit protein uL4c; |
| Gene name | Name=rpl4; |
| end case | |
Comments
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| case not <OG:Chloroplast> | |
| FUNCTION | One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. |
| FUNCTION | Forms part of the polypeptide exit tunnel. |
| SUBUNIT | Part of the 50S ribosomal subunit. |
| else case <OG:Chloroplast> | |
| FUNCTION | Probably binds the 23S rRNA. |
| SUBUNIT | Part of the 50S ribosomal subunit. |
| SUBCELLULAR LOCATION | Plastid, chloroplast. |
| end case | |
| SIMILARITY | Belongs to the universal ribosomal protein uL4 family. |
Keywords
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Gene Ontology
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| GO:0019843; Molecular function:rRNA binding | |
| GO:0006412; Biological process:translation | |
| case <OG:Chloroplast> | |
| GO:0009507; Cellular component:chloroplast | |
| end case | |
Cross-references
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| Pfam | PF00573; Ribosomal_L4; 1; |
| NCBIfam | TIGR03953; rplD_bact; 1; |
| NCBIfam | TIGR03672; rpl4p_arch; 1; |
| PROSITE | PS00939; RIBOSOMAL_L1E; 1; |
Features
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Additional information
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| Size range | 246-283 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: <Unknown> |
| Comments | Fused with unknown domains in CUTAK, SYNJA, SYNJB |