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HAMAP rule MF_01330

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General rule information [?]

Accession MF_01330
Dates 20-APR-2004 (Created)
19-NOV-2022 (Last updated, Version 28)
Name Ycf2
Template P09976 (YCF2_TOBAC)

Propagated annotation [?]

Identifier, protein and gene names [?]

Protein name
RecName: Full=Protein Ycf2;
Gene name

Comments [?]

Function Probable ATPase of unknown function. Its presence in a non-photosynthetic plant (Epifagus virginiana) and experiments in tobacco indicate that it has an essential function which is probably not related to photosynthesis.
Subcellular location Plastid, chloroplast stroma.
Similarity Belongs to the Ycf2 family.

Keywords [?]

Gene Ontology [?]

case <OG:Chloroplast>
GO:0009570; Cellular component: chloroplast stroma.
end case

Cross-references [?]

Pfam PF05695; DUF825; 1;
PF00004; AAA; 1;

Features [?]

From: YCF2_TOBAC (P09976)
Key     From     To       Description   Tag   Condition   FTGroup
BINDING     1631     1638       /ligand="ATP" /ligand_id="ChEBI:CHEBI:30616     G-x(4)-G-[KR]-S  

Additional information [?]

Size range 1974-2434 amino acids
Related rules None
Fusion None
Comments Has been suggested to be a proteolytic ATPase. The most conserved regions are in the C-terminus and are similar to the Walker A, B and AAA motifs, see: PubMed=8082182; Wolfe K.H.; "Similarity between putative ATP-binding sites in land plant plastid ORF2280 proteins and the FtsH/CDC48 family of ATPases."; Curr. Genet. 25:379-383(1994). This protein is poorly conserved in sequence and tolerates numerous inserts and deletions. It has suffered major deletions in at least some members of the Passifloraceae, Geraniaceae, Cuscutaceae, Campanulaceae and Poaceae (the grasses); however it seems to be intact in other land plants, see: MEDLINE=94363755; PubMed=8082181; Downie S.R., Katz-Downie D.S., Wolfe K.H., Calie P.J., Palmer J.D.; "Structure and evolution of the largest chloroplast gene (ORF2280): internal plasticity and multiple gene loss during angiosperm evolution."; Curr. Genet. 25:367-378(1994).