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Annotation rule MF_01331
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General rule information [?]

Accession MF_01331
Dates 1-JUL-2004 (Created)
19-NOV-2019 (Last updated, Version 26)
Name Ribosomal_L22
Scope
Bacteria
Archaea
Plastid
Templates Q9RXJ7 (RL22_DEIRA); P61175 (RL22_ECOLI); P48286 (RL22_THETH); Q5SHP3 (RL22_THET8); P10970 (RL22_HALMA): [Recover all]
case <OC:Bacteria> or <OG:Chloroplast>
Triggered by
end case

case <OC:Archaea>
Triggered by
end case


Propagated annotation [?]


Identifier, protein and gene names [?]

case <OC:Bacteria> and not <OC:Cyanobacteria>
Identifier
RL22
Protein name
RecName: Full=50S ribosomal protein L22;
Gene name
rplV
else case <OC:Cyanobacteria>
Identifier
RL22
Protein name
RecName: Full=50S ribosomal protein L22;
Gene name
rplV, rpl22
else case <OC:Archaea>
Identifier
RL22
Protein name
RecName: Full=50S ribosomal protein L22;
Gene name
rpl22
else case <OG:Chloroplast>
Identifier
RK22
Protein name
RecName: Full=50S ribosomal protein L22, chloroplastic;
Gene name
rpl22
end case

Comments [?]

case <OC:Bacteria>
Function This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
else case <OC:Archaea>
Function This protein binds specifically to 23S rRNA. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
else case <OG:Chloroplast>
Function This protein binds specifically to 23S rRNA.
end case
Function The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
Subunit Part of the 50S ribosomal subunit.
case <OG:Chloroplast>
Subcellular location Plastid, chloroplast.
end case
Similarity Belongs to the universal ribosomal protein uL22 family.

Keywords [?]

Ribonucleoprotein
Ribosomal protein
RNA-binding
rRNA-binding

Gene Ontology [?]

GO:0019843; Molecular function: rRNA binding.
GO:0006412; Biological process: translation.
case <OG:Chloroplast>
GO:0009507; Cellular component: chloroplast.
end case

Cross-references [?]

Pfam PF00237; Ribosomal_L22; 1;
TIGRFAMs TIGR01044; RplV_bact; 1;
TIGR01038; L22_arch; 1;
PROSITE PS00464; RIBOSOMAL_L22; 1;

Additional information [?]

case <OC:Bacteria> or <OG:Chloroplast>
Size range 105-210 amino acids
end case
case <OC:Archaea>
Size range 148-185 amino acids
end case
Related rules None
Fusion Nter: None; Cter: <Unknown>
Comments C-terminal fusion to an unknown domain in ACIC1, UREPA, UREP2. Plastid-encoded in most land plants; however it is nuclearly encoded in the Fabaceae.


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