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HAMAP rule MF_01339

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General rule information [?]

Accession MF_01339
Dates 8-NOV-2005 (Created)
19-NOV-2022 (Last updated, Version 20)
Name RuBisCO_L_type2
Bacteria; Rhodopseudomonas
Bacteria; Rhodobacterales
Bacteria; Rhodospirillales
Bacteria; Comamonadaceae
Bacteria; Thiomonas
Bacteria; Hydrogenophilales
Bacteria; Rhodocyclaceae
Bacteria; Halothiobacillus
Bacteria; Hydrogenovibrio
Bacteria; Thiomicrospira
Template P04718 (RBL2_RHORU)

Propagated annotation [?]

Identifier, protein and gene names [?]

Protein name
RecName: Full=Ribulose bisphosphate carboxylase;
Gene name

Comments [?]

Function RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site.
Catalytic activity RHEA:23124: 2 (2R)-3-phosphoglycerate + 2 H(+) = CO2 + D-ribulose 1,5-bisphosphate + H2O
RHEA:36631: D-ribulose 1,5-bisphosphate + O2 = (2R)-3-phosphoglycerate + 2-phosphoglycolate + 2 H(+)
case <FTGroup:1>
Cofactor Mg(2+)
Note: Binds 1 Mg(2+) ion per subunit.
end case
Subunit Homodimer.
Miscellaneous The basic functional RuBisCO is composed of a large chain homodimer in a 'head-to-tail' conformation. In contrast to form I RuBisCO, the form II RuBisCO are composed solely of large subunits.
Similarity Belongs to the RuBisCO large chain family. Type II subfamily.

Keywords [?]

case <FTGroup:1>
end case
case <Property:PHOTOSYN>
end case

Gene Ontology [?]

case <FTGroup:1>
GO:0000287; Molecular function: magnesium ion binding.
end case
GO:0016984; Molecular function: ribulose-bisphosphate carboxylase activity.

Cross-references [?]

Pfam PF00016; RuBisCO_large; 1;
PF02788; RuBisCO_large_N; 1;

Features [?]

From: RBL2_RHORU (P04718)
Key     From     To       Description   Tag   Condition   FTGroup
ACT_SITE     166     166       Proton acceptor     K  
ACT_SITE     287     287       Proton acceptor     H  
BINDING     191     191       /ligand="Mg(2+)" /ligand_id="ChEBI:CHEBI:18420" /note="via carbamate group     K   1
BINDING     193     193       /ligand="Mg(2+)" /ligand_id="ChEBI:CHEBI:18420     D   1
BINDING     194     194       /ligand="Mg(2+)" /ligand_id="ChEBI:CHEBI:18420     E   1
SITE     329     329       Transition state stabilizer     K  
BINDING     111     111       /ligand="substrate" /note="in homodimeric partner     N  
BINDING     168     168       /ligand="substrate     K  
BINDING     288     288       /ligand="substrate     R  
BINDING     321     321       /ligand="substrate     H  
BINDING     368     368       /ligand="substrate     S  
MOD_RES     191     191       N6-carboxylysine     K  

Additional information [?]

Size range 458-466 amino acids
Related rules MF_01133 (RBL); MF_01338 (RBL)
Fusion None