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HAMAP rule MF_01339

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General rule information [?]

Accession MF_01339
Dates 8-NOV-2005 (Created)
19-NOV-2022 (Last updated, Version 20)
Name RuBisCO_L_type2
Scope(s) Bacteria
Rhodopseudomonas
Rhodobacterales
Rhodospirillales
Comamonadaceae
Thiomonas
Hydrogenophilales
Rhodocyclaceae
Halothiobacillus
Hydrogenovibrio
Thiomicrospira
Template(s) P04718 (RBL2_RHORU); [ Recover all ]
Triggered by HAMAP; MF_01339 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier RBL2
Protein name RecName: Full=Ribulose bisphosphate carboxylase;
                 Short=RuBisCO;
                 EC=4.1.1.39;
Gene name Name=cbbM;

Comments [?]

FUNCTIONRuBisCO catalyzes two reactions: the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site.
CATALYTIC ACTIVITY Reaction=2 (2R)-3-phosphoglycerate + 2 H(+) = CO2 + D-ribulose 1,5- bisphosphate + H2O; Xref=Rhea:RHEA:23124, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:16526, ChEBI:CHEBI:57870, ChEBI:CHEBI:58272; EC=4.1.1.39;
CATALYTIC ACTIVITY Reaction=D-ribulose 1,5-bisphosphate + O2 = (2R)-3-phosphoglycerate + 2-phosphoglycolate + 2 H(+); Xref=Rhea:RHEA:36631, ChEBI:CHEBI:15378, ChEBI:CHEBI:15379, ChEBI:CHEBI:57870, ChEBI:CHEBI:58033, ChEBI:CHEBI:58272;
case <FTGroup:1>
COFACTOR Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Note=Binds 1 Mg(2+) ion per subunit.;
end case
SUBUNITHomodimer.
MISCELLANEOUSThe basic functional RuBisCO is composed of a large chain homodimer in a 'head-to-tail' conformation. In contrast to form I RuBisCO, the form II RuBisCO are composed solely of large subunits.
SIMILARITYBelongs to the RuBisCO large chain family. Type II subfamily.

Keywords [?]

Calvin cycle
Carbon dioxide fixation
Lyase
case <FTGroup:1>
Magnesium
Metal-binding
end case
Monooxygenase
Oxidoreductase
case <Property:PHOTOSYN>
Photosynthesis
end case

Gene Ontology [?]

case <FTGroup:1>
GO:0000287; Molecular function:magnesium ion binding
end case
GO:0016984; Molecular function:ribulose-bisphosphate carboxylase activity

Cross-references [?]

PROSITE PS00157; RUBISCO_LARGE; 1;
Pfam PF00016; RuBisCO_large; 1;
Pfam PF02788; RuBisCO_large_N; 1;

Features [?]

From: RBL2_RHORU (P04718)
Key From To Description Tag Condition FTGroup
ACT_SITE 166 166 /note="Proton acceptor" K
ACT_SITE 287 287 /note="Proton acceptor" H
BINDING 191 191 /ligand="Mg(2+)"
/ligand_id="ChEBI:CHEBI:18420"
/note="via carbamate group"
K 1
BINDING 193 193 /ligand="Mg(2+)"
/ligand_id="ChEBI:CHEBI:18420"
D 1
BINDING 194 194 /ligand="Mg(2+)"
/ligand_id="ChEBI:CHEBI:18420"
E 1
SITE 329 329 /note="Transition state stabilizer" K
BINDING 111 111 /ligand="substrate"
/note="in homodimeric partner"
N
BINDING 168 168 /ligand="substrate" K
BINDING 288 288 /ligand="substrate" R
BINDING 321 321 /ligand="substrate" H
BINDING 368 368 /ligand="substrate" S
MOD_RES 191 191 /note="N6-carboxylysine" K

Additional information [?]

Size range 458-466 amino acids
Related rules MF_01133
MF_01338
Fusion Nter: None Cter: None



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