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HAMAP rule MF_01352

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General rule information [?]

Accession MF_01352
Dates 4-SEP-2008 (Created)
15-JUN-2023 (Last updated, Version 16)
Bacteria; Cyanobacteriota
Template P74338 (NDHM_SYNY3)

Propagated annotation [?]

Identifier, protein and gene names [?]

Protein name
RecName: Full=NAD(P)H-quinone oxidoreductase subunit M;
EC 7.1.1.-;
AltName: Full=NAD(P)H dehydrogenase I subunit M;
Short=NDH-1 subunit M;
Gene name

Comments [?]

Function NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.
Catalytic activity RHEA:42608: a plastoquinone + (n+1) H(+)(in) + NADH = a plastoquinol + n H(+)(out) + NAD(+)
RHEA:42612: a plastoquinone + (n+1) H(+)(in) + NADPH = a plastoquinol + n H(+)(out) + NADP(+)
Subunit NDH-1 can be composed of about 15 different subunits; different subcomplexes with different compositions have been identified which probably have different functions.
case <OC:Gloeobacter>
Subcellular location Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Subcellular location Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side.
end case
Similarity Belongs to the complex I NdhM subunit family.

Keywords [?]

case <OC:Gloeobacter>
end case

Gene Ontology [?]

GO:0016655; Molecular function: oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor.
case <OC:Gloeobacter>
GO:0005886; Cellular component: plasma membrane.
GO:0042651; Cellular component: thylakoid membrane.
end case

Cross-references [?]

Pfam PF10664; NdhM; 1;

Additional information [?]

Size range 109-148 amino acids
Related rules None
Fusion None
Comments One of a number of subunits unique to cyanoabacteria and plastids, it is nuclearly encoded in angiosperms.