HAMAP rule MF_01354
General rule information
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| Accession | MF_01354 |
| Dates | 4-SEP-2008 (Created)
15-JUN-2023 (Last updated, Version 15) |
| Name | NDH1_NDH1O |
| Scope(s) |
Bacteria Cyanobacteriota Plastid |
| Template(s) | P74771 (NDHO_SYNY3); [ Recover all ] |
| Triggered by |
HAMAP; MF_01354 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | NDHO |
| Protein name | RecName: Full=NAD(P)H-quinone oxidoreductase subunit O; EC=7.1.1.-; AltName: Full=NAD(P)H dehydrogenase I subunit O; Short=NDH-1 subunit O; Short=NDH-O; |
| Gene name | Name=ndhO; |
Comments
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| FUNCTION | NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration. |
| CATALYTIC ACTIVITY | Reaction=a plastoquinone + (n+1) H(+)(in) + NADH = a plastoquinol + n H(+)(out) + NAD(+); Xref=Rhea:RHEA:42608, Rhea:RHEA-COMP:9561, Rhea:RHEA-COMP:9562, ChEBI:CHEBI:15378, ChEBI:CHEBI:17757, ChEBI:CHEBI:57540, ChEBI:CHEBI:57945, ChEBI:CHEBI:62192; |
| CATALYTIC ACTIVITY | Reaction=a plastoquinone + (n+1) H(+)(in) + NADPH = a plastoquinol + n H(+)(out) + NADP(+); Xref=Rhea:RHEA:42612, Rhea:RHEA-COMP:9561, Rhea:RHEA-COMP:9562, ChEBI:CHEBI:15378, ChEBI:CHEBI:17757, ChEBI:CHEBI:57783, ChEBI:CHEBI:58349, ChEBI:CHEBI:62192; |
| SUBUNIT | NDH-1 can be composed of about 15 different subunits; different subcomplexes with different compositions have been identified which probably have different functions. |
| case <OC:Gloeobacter> | |
| SUBCELLULAR LOCATION | Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. |
| else | |
| SUBCELLULAR LOCATION | Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side. |
| end case | |
| SIMILARITY | Belongs to the complex I NdhO subunit family. |
Keywords
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| Membrane | |
| NAD | |
| NADP | |
| Plastoquinone | |
| Quinone | |
| Transport | |
| case <OC:Gloeobacter> | |
| Cell membrane | |
| Cell inner membrane | |
| else | |
| Thylakoid | |
| end case | |
| <a href="https://www.uniprot.org/keywords/KW-1278">Translocase</a> | |
Gene Ontology
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| GO:0016655; Molecular function:oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor | |
| case <OCellular component:Gloeobacter> | |
| GO:0005886; Cellular component:plasma membrane | |
| else; https://www.ebi.ac.uk/QuickGO/term/else | |
| GO:0042651; Cellular component:thylakoid membrane | |
| end case | |
Cross-references
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Features
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Additional information
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| Size range | 70-87 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |
| Comments | One of a number of subunits unique to cyanobacteria and plastids, it is nuclearly encoded in angiosperms. |