HAMAP rule MF_01354

General rule information [?]

Accession	MF_01354
Dates	4-SEP-2008 (Created) 15-JUN-2023 (Last updated, Version 15)

Name	NDH1_NDH1O

Scope

Bacteria; Cyanobacteriota

Plastid

Template

P74771 (NDHO_SYNY3)

Triggered by

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier

NDHO

Protein name

RecName:		Full=NAD(P)H-quinone oxidoreductase subunit O;
		EC 7.1.1.-;
AltName:		Full=NAD(P)H dehydrogenase I subunit O;
		Short=NDH-1 subunit O;
		Short=NDH-O;

Gene name

ndhO

Comments [?]

Function	NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.
Catalytic activity	RHEA:42608: a plastoquinone + (n+1) H(+)(in) + NADH = a plastoquinol + n H(+)(out) + NAD(+)
	RHEA:42612: a plastoquinone + (n+1) H(+)(in) + NADPH = a plastoquinol + n H(+)(out) + NADP(+)
Subunit	NDH-1 can be composed of about 15 different subunits; different subcomplexes with different compositions have been identified which probably have different functions.

case <OC:Gloeobacter>

Subcellular location

Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.

else

Subcellular location

Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side.

end case

Similarity

Belongs to the complex I NdhO subunit family.

Keywords [?]

case <OC:Gloeobacter>

else

end case

Gene Ontology [?]

GO:0016655; Molecular function: oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor.

case <OC:Gloeobacter>

GO:0005886; Cellular component: plasma membrane.

else

GO:0042651; Cellular component: thylakoid membrane.

end case

Additional information [?]

Size range	70-87 amino acids
Related rules	None
Fusion	None
Comments	One of a number of subunits unique to cyanobacteria and plastids, it is nuclearly encoded in angiosperms.