HAMAP rule MF_01355

Accession	MF_01355
Dates	8-SEP-2008 (Created) 15-JUN-2023 (Last updated, Version 17)

Name	NDH1_NDH1L

Scope

Bacteria; Cyanobacteriota Plastid

Template

P27372 (NDHL_SYNY3)

Triggered by

HAMAP; MF_01355 (Get profile general information and statistics)

Identifier

NDHL

Protein name

RecName: Full=NAD(P)H-quinone oxidoreductase subunit L; EC 7.1.1.-; AltName: Full=NAD(P)H dehydrogenase I subunit L; Short=NDH-1 subunit L; Short=NDH-L;

Gene name

ndhL

Function	NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.
Catalytic activity	RHEA:42608: a plastoquinone + (n+1) H(+)(in) + NADH = a plastoquinol + n H(+)(out) + NAD(+)
	RHEA:42612: a plastoquinone + (n+1) H(+)(in) + NADPH = a plastoquinol + n H(+)(out) + NADP(+)
Subunit	NDH-1 can be composed of about 15 different subunits; different subcomplexes with different compositions have been identified which probably have different functions.
Subcellular location	Cellular thylakoid membrane; Multi-pass membrane protein.
Similarity	Belongs to the complex I NdhL subunit family.

Membrane
NAD
NADP
Plastoquinone
Quinone
Transmembrane
Transport
Thylakoid
Transmembrane helix
Translocase

GO:0016655; Molecular function: oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor.
GO:0042651; Cellular component: thylakoid membrane.

General

Transmembrane; -; 2; trigger=yes;

Size range	69-89 amino acids
Related rules	None
Fusion	None
Comments	One of a number of subunits unique to cyanobacteria and plastids, it is nuclearly encoded in angiosperms.

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