Home  |  Contact
Annotation rule MF_01381
Send feedback

General rule information [?]

Accession MF_01381
Dates 12-NOV-2007 (Created)
19-NOV-2019 (Last updated, Version 17)
Name EmtA
Scope
Bacteria; Enterobacterales
Template P0C960 (EMTA_ECOLI)

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
EMTA
Protein name
RecName: Full=Endo-type membrane-bound lytic murein transglycosylase A;
EC 4.2.2.n2;
AltName: Full=Peptidoglycan lytic endotransglycosylase;
Flags: Precursor;
Gene name
emtA

Comments [?]

Function Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division. Preferentially cleaves at a distance of more than two disaccharide units from the ends of the glycan chain.
Catalytic activity Reaction=Endolytic cleavage of the (1->4)-beta-glycosidic linkage between N-acetylmuramic acid (MurNAc) and N-acetylglucosamine (GlcNAc) residues in peptidoglycan with concomitant formation of a 1,6-anhydrobond in the MurNAc residue.; EC=4.2.2.n2;
Subcellular location Cell outer membrane; Lipid-anchor.
Similarity Belongs to the transglycosylase Slt family.

Keywords [?]

case <Feature:PS51257>
end case

Gene Ontology [?]

GO:0016837; Molecular function: carbon-oxygen lyase activity, acting on polysaccharides.
GO:0016998; Biological process: cell wall macromolecule catabolic process.
GO:0009279; Cellular component: cell outer membrane.

Cross-references [?]

PROSITE PS51257; PROKAR_LIPOPROTEIN; 1; trigger=PRU00303;
PS00922; TRANSGLYCOSYLASE; 1;
Pfam PF01464; SLT; 1;

Additional information [?]

Size range 203-219 amino acids
Related rules None
Fusion None
Comments Due to a small duplication there is a second copy in SHIFL 301 / Serotype 2a that does not have a lipobox and is annotated as atypical.