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HAMAP rule MF_01393

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General rule information [?]

PURL https://purl.expasy.org/hamap/rule/MF_01393
Accession MF_01393
Dates 28-NOV-2008 (Created)
07-DEC-2023 (Last updated, Version 26)
Name ATP_synth_a_bact
Scope(s) Bacteria
Plastid
Template(s) P0AB98; P06451; [ Recover all ]
Triggered by
case c? <OC:Bacteria> or <OG:Chloroplast>
HAMAP; MF_01393 (Get profile general information and statistics)
end case

Propagated annotation [?]

Identifier, protein and gene names [?]

case <OC:Bacteria>
Identifier ATP6
Protein name RecName: Full=ATP synthase subunit a;
AltName: Full=ATP synthase F0 sector subunit a;
AltName: Full=F-ATPase subunit 6;
else case <OG:Chloroplast>
Identifier ATPI
Protein name RecName: Full=ATP synthase subunit a, chloroplastic;
AltName: Full=ATP synthase F0 sector subunit a;
AltName: Full=F-ATPase subunit IV;
end case
case <OC:Cyanobacteriota>
Gene name Name=atpB; Synonyms=atpI;
else case <OG:Chloroplast>
Gene name Name=atpI;
else
Gene name Name=atpB;
end case

Comments [?]

FUNCTIONKey component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
case <OG:Chloroplast> or <Property:PHOTOSYN>
SUBUNITF-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a, b, b' and c.
else
SUBUNITF-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
end case
case <OG:Chloroplast>
SUBCELLULAR LOCATIONPlastid, chloroplast thylakoid membrane; Multi- pass membrane protein.
else case <OC:Cyanobacteriota> and not <OC:Gloeobacter>
SUBCELLULAR LOCATIONCellular thylakoid membrane; Multi-pass membrane protein.
else case <OC:Gloeobacter>
SUBCELLULAR LOCATIONCell inner membrane; Multi-pass membrane protein.
else case not defined <Property:Membrane> or <Property:Membrane=1>
SUBCELLULAR LOCATIONCell membrane; Multi-pass membrane protein.
else case <Property:Membrane=2>
SUBCELLULAR LOCATIONCell inner membrane; Multi-pass membrane protein.
end case
SIMILARITYBelongs to the ATPase A chain family.

Keywords [?]

ATP synthesis
CF(0)
Hydrogen ion transport
Ion transport
Membrane
Transmembrane
Transport
case <OG:Chloroplast> or <OC:Cyanobacteriota> and not <OC:Gloeobacter>
Thylakoid
else case <OC:Gloeobacter>
Cell membrane
Cell inner membrane
else case not defined <Property:Membrane> or <Property:Membrane=1>
Cell membrane
else case <Property:Membrane=2>
Cell membrane
Cell inner membrane
end case
Transmembrane helix

Gene Ontology [?]

GO:0046933; Molecular function:proton-transporting ATP synthase activity, rotational mechanism
GO:0015986; Biological process:proton motive force-driven ATP synthesis
case <OCellular component:Cyanobacteriota> and not <OC:Gloeobacter>
GO:0042651; Cellular component:thylakoid membrane
else; https://www.ebi.ac.uk/QuickGO/term/else
GO:0005886; Cellular component:plasma membrane
end case
case <OG:Chloroplast>
GO:0009535; Cellular component:chloroplast thylakoid membrane
end case

Cross-references [?]

PROSITE PS00449; ATPASE_A; 1;
Pfam PF00119; ATP-synt_A; 1;
PRINTS PR00123; ATPASEA; 1;
NCBIfam TIGR01131; ATP_synt_6_or_A; 1;
General Transmembrane; -; 4-8;

Features [?]


Additional information [?]

Size range 207-406 amino acids
Related rules None
Fusion Nter: None Cter: None
Comments In Anaeromyxobacter and some of the Chlorobiota the protein could have a signal sequence; these proteins have a considerably longer N- terminus compared to other family members.



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