HAMAP rule MF_01410
General rule information
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| PURL | https://purl.expasy.org/hamap/rule/MF_01410 |
| Accession | MF_01410 |
| Dates | 28-FEB-2005 (Created)
19-NOV-2022 (Last updated, Version 21) |
| Name | G6P_isomerase_arch |
| Scope(s) |
Bacteria Archaea |
| Template(s) | P84140; P83194; [ Recover all ] |
| Triggered by |
HAMAP; MF_01410 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | GPI |
| Protein name | RecName: Full=Glucose-6-phosphate isomerase; Short=GPI; EC=5.3.1.9; AltName: Full=Phosphoglucose isomerase; Short=PGI; AltName: Full=Phosphohexose isomerase; Short=PHI; |
| Gene name | Name=pgiA; |
Comments
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| CATALYTIC ACTIVITY | Reaction=alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate; Xref=Rhea:RHEA:11816, ChEBI:CHEBI:57634, ChEBI:CHEBI:58225; EC=5.3.1.9; |
| PATHWAY | Carbohydrate degradation; glycolysis; D-glyceraldehyde 3- phosphate and glycerone phosphate from D-glucose: step 2/4. |
| SUBUNIT | Homodimer. |
| SUBCELLULAR LOCATION | Cytoplasm. |
| SIMILARITY | Belongs to the archaeal-type GPI family. |
Keywords
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| Cytoplasm | |
| Isomerase | |
| Gluconeogenesis | |
| Glycolysis | |
| case <FTGroup:1> | |
| Iron | |
| Metal-binding | |
| end case | |
Gene Ontology
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| GO:0004347; Molecular function:glucose-6-phosphate isomerase activity |
| GO:0006094; Biological process:gluconeogenesis |
| GO:0006096; Biological process:glycolytic process |
| GO:0005737; Cellular component:cytoplasm |
Cross-references
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| Pfam | PF06560; GPI; 1; |
Features
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| From: G6PI_THELI (P84140) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| BINDING | 89 | 89 | /ligand="Fe cation" /ligand_id="ChEBI:CHEBI:24875" |
H | 1 | |||||||
| BINDING | 91 | 91 | /ligand="Fe cation" /ligand_id="ChEBI:CHEBI:24875" |
H | 1 | |||||||
| BINDING | 98 | 98 | /ligand="Fe cation" /ligand_id="ChEBI:CHEBI:24875" |
E | 1 | |||||||
| BINDING | 137 | 137 | /ligand="Fe cation" /ligand_id="ChEBI:CHEBI:24875" |
H | 1 | |||||||
Additional information
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| Size range | 189-214 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |