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Annotation rule MF_01412
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General rule information [?]

Accession MF_01412
Dates 2-OCT-2003 (Created)
19-NOV-2019 (Last updated, Version 26)
Name K_H_efflux_KefB
Scope
Bacteria; Gammaproteobacteria
Template P45522 (KEFB_ECOLI)
Triggered by

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
KEFB
Protein name
RecName: Full=Glutathione-regulated potassium-efflux system protein KefB;
AltName: Full=K(+)/H(+) antiporter;
Gene name
kefB

Comments [?]

Function Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport.
Subunit Interacts with the regulatory subunit KefG.
Subcellular location Cell inner membrane; Multi-pass membrane protein.
Similarity Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. KefB subfamily.

Keywords [?]

Transport
Antiport
Ion transport
Potassium
Potassium transport
Transmembrane
Membrane
Cell membrane
Cell inner membrane
Transmembrane helix

Gene Ontology [?]

GO:0015503; Molecular function: glutathione-regulated potassium exporter activity.
GO:0006813; Biological process: potassium ion transport.
GO:0005887; Cellular component: integral component of plasma membrane.

Cross-references [?]

Pfam PF00999; Na_H_Exchanger; 1;
PF02254; TrkA_N; 1;
PRINTS PR00335; KUPTAKETRKA; 1;
TIGRFAMs TIGR00932; 2a37; 1;
PROSITE PS51201; RCK_N; 1; trigger=PRU00543;

Computed features [?]

General Transmembrane; -; 10-13; trigger=yes;

Additional information [?]

Size range 544-656 amino acids
Related rules None
Fusion None


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