HAMAP logo

HAMAP rule MF_01412

Send feedback

General rule information [?]

Accession MF_01412
Dates 2-OCT-2003 (Created)
1-JUN-2023 (Last updated, Version 28)
Name K_H_efflux_KefB
Scope(s) Bacteria
Template(s) P45522 (KEFB_ECOLI); [ Recover all ]
Triggered by HAMAP; MF_01412 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier KEFB
Protein name RecName: Full=Glutathione-regulated potassium-efflux system protein KefB;
AltName: Full=K(+)/H(+) antiporter;
Gene name Name=kefB;

Comments [?]

FUNCTIONPore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport.
SUBUNITInteracts with the regulatory subunit KefG.
SUBCELLULAR LOCATIONCell inner membrane; Multi-pass membrane protein.
SIMILARITYBelongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. KefB subfamily.

Keywords [?]

Gene Ontology [?]

GO:0015503; Molecular function:glutathione-regulated potassium exporter activity
GO:0006813; Biological process:potassium ion transport
GO:0005886; Cellular component:plasma membrane

Cross-references [?]

Pfam PF00999; Na_H_Exchanger; 1;
Pfam PF02254; TrkA_N; 1;
NCBIfam TIGR00932; 2a37; 1;
PROSITE PS51201; RCK_N; 1;
General Transmembrane; -; 10-13;

Features [?]

Additional information [?]

Size range 544-656 amino acids
Related rules None
Fusion Nter: None Cter: None

View rule in raw text format (no links)