HAMAP rule MF_01412
General rule information
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Accession | MF_01412 |
Dates | 2-OCT-2003 (Created)
1-JUN-2023 (Last updated, Version 28) |
Name | K_H_efflux_KefB |
Scope(s) |
Bacteria Gammaproteobacteria |
Template(s) | P45522 (KEFB_ECOLI); [ Recover all ] |
Triggered by |
HAMAP; MF_01412 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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Identifier | KEFB |
Protein name | RecName: Full=Glutathione-regulated potassium-efflux system protein KefB; AltName: Full=K(+)/H(+) antiporter; |
Gene name | Name=kefB; |
Comments
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FUNCTION | Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport. |
SUBUNIT | Interacts with the regulatory subunit KefG. |
SUBCELLULAR LOCATION | Cell inner membrane; Multi-pass membrane protein. |
SIMILARITY | Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. KefB subfamily. |
Keywords
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Transport |
Antiport |
Ion transport |
Potassium |
Potassium transport |
Transmembrane |
Membrane |
Cell membrane |
Cell inner membrane |
Transmembrane helix |
Gene Ontology
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GO:0015503; Molecular function:glutathione-regulated potassium exporter activity |
GO:0006813; Biological process:potassium ion transport |
GO:0005886; Cellular component:plasma membrane |
Cross-references
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Pfam | PF00999; Na_H_Exchanger; 1; |
Pfam | PF02254; TrkA_N; 1; |
PRINTS | PR00335; KUPTAKETRKA; 1; |
NCBIfam | TIGR00932; 2a37; 1; |
PROSITE | PS51201; RCK_N; 1; |
General | Transmembrane; -; 10-13; |
Features
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Additional information
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Size range | 544-656 amino acids |
Related rules |
None |
Fusion | Nter: None Cter: None |