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Annotation rule MF_01422
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General rule information [?]

Accession MF_01422
Dates 2-FEB-2005 (Created)
19-NOV-2019 (Last updated, Version 18)
Name MdtA
Scope
Bacteria; Enterobacterales
Template P76397 (MDTA_ECOLI)
Triggered by

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
MDTA
Protein name
RecName: Full=Multidrug resistance protein MdtA;
AltName: Full=Multidrug transporter MdtA;
Flags: Precursor;
Gene name
mdtA

Comments [?]

case <OC:Escherichia>
Function The MdtABC tripartite complex confers resistance against novobiocin and deoxycholate.
end case
Subunit Part of a tripartite efflux system composed of MdtA, MdtB and MdtC.
Subcellular location Cell inner membrane; Peripheral membrane protein.
case <OC:Escherichia>
Induction The mdtABC operon is transcriptionally activated by BaeR.
end case
Similarity Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

Keywords [?]

Cell membrane
Cell inner membrane
Membrane
Transport

Gene Ontology [?]

GO:0022857; Molecular function: transmembrane transporter activity.
GO:0005886; Cellular component: plasma membrane.

Cross-references [?]

Pfam PF00529; HlyD; 1;
TIGRFAMs TIGR01730; RND_mfp; 1;

Computed features [?]

General Signal; -; 1; trigger=yes;

Additional information [?]

Size range 401-444 amino acids
Related rules None
Fusion None
Comments The sequence of Shigella flexneri is shorter but it is impossible to correct the sequence.


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