HAMAP logo

HAMAP rule MF_01422

Send feedback

General rule information [?]

Accession MF_01422
Dates 2-FEB-2005 (Created)
1-JUN-2023 (Last updated, Version 19)
Name MdtA
Scope(s) Bacteria
Template(s) P76397 (MDTA_ECOLI); [ Recover all ]
Triggered by HAMAP; MF_01422 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier MDTA
Protein name RecName: Full=Multidrug resistance protein MdtA;
AltName: Full=Multidrug transporter MdtA;
                 Flags: Precursor;
Gene name Name=mdtA;

Comments [?]

case <OC:Escherichia>
FUNCTIONThe MdtABC tripartite complex confers resistance against novobiocin and deoxycholate.
end case
SUBUNITPart of a tripartite efflux system composed of MdtA, MdtB and MdtC.
SUBCELLULAR LOCATIONCell inner membrane; Peripheral membrane protein.
case <OC:Escherichia>
INDUCTIONThe mdtABC operon is transcriptionally activated by BaeR.
end case
SIMILARITYBelongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

Keywords [?]

Gene Ontology [?]

GO:0022857; Molecular function:transmembrane transporter activity
GO:0005886; Cellular component:plasma membrane

Cross-references [?]

Pfam PF00529; HlyD; 1;
NCBIfam TIGR01730; RND_mfp; 1;
General Signal; -; 1;

Features [?]

Additional information [?]

Size range 401-444 amino acids
Related rules None
Fusion Nter: None Cter: None
Comments The sequence of Shigella flexneri is shorter but it is impossible to correct the sequence.

View rule in raw text format (no links)