HAMAP rule MF_01422
General rule information
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Accession | MF_01422 |
Dates | 2-FEB-2005 (Created)
1-JUN-2023 (Last updated, Version 19) |
Name | MdtA |
Scope(s) |
Bacteria Enterobacterales |
Template(s) | P76397 (MDTA_ECOLI); [ Recover all ] |
Triggered by |
HAMAP; MF_01422 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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Identifier | MDTA |
Protein name | RecName: Full=Multidrug resistance protein MdtA; AltName: Full=Multidrug transporter MdtA; Flags: Precursor; |
Gene name | Name=mdtA; |
Comments
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case <OC:Escherichia> | |
FUNCTION | The MdtABC tripartite complex confers resistance against novobiocin and deoxycholate. |
end case | |
SUBUNIT | Part of a tripartite efflux system composed of MdtA, MdtB and MdtC. |
SUBCELLULAR LOCATION | Cell inner membrane; Peripheral membrane protein. |
case <OC:Escherichia> | |
INDUCTION | The mdtABC operon is transcriptionally activated by BaeR. |
end case | |
SIMILARITY | Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. |
Keywords
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Gene Ontology
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GO:0022857; Molecular function:transmembrane transporter activity |
GO:0005886; Cellular component:plasma membrane |
Cross-references
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Features
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Additional information
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Size range | 401-444 amino acids |
Related rules |
None |
Fusion | Nter: None Cter: None |
Comments | The sequence of Shigella flexneri is shorter but it is impossible to correct the sequence. |