HAMAP rule MF_01423

General rule information [?]

Accession	MF_01423
Dates	2-FEB-2005 (Created) 19-NOV-2019 (Last updated, Version 22)
Name	MdtB
Scope(s)	Bacteria Enterobacterales
Template(s)	P76398 (MDTB_ECOLI); [ Recover all ]
Triggered by	HAMAP; MF_01423 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier	MDTB
Protein name	RecName: Full=Multidrug resistance protein MdtB; AltName: Full=Multidrug transporter MdtB;
Gene name	Name=mdtB;

Comments [?]

case <OC:Escherichia>
FUNCTION	The MdtABC tripartite complex confers resistance against novobiocin and deoxycholate.
end case
SUBUNIT	Part of a tripartite efflux system composed of MdtA, MdtB and MdtC. MdtB forms a heteromultimer with MdtC.
SUBCELLULAR LOCATION	Cell inner membrane; Multi-pass membrane protein.
case <OC:Escherichia>
INDUCTION	The mdtABC operon is transcriptionally activated by BaeR.
end case
SIMILARITY	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtB subfamily.

Keywords [?]

Gene Ontology [?]

GO:0022857; Molecular function:transmembrane transporter activity

GO:0005886; Cellular component:plasma membrane

Cross-references [?]

Features [?]

Additional information [?]

Size range	1039-1056 amino acids
Related rules	None
Fusion	Nter: None Cter: None
Comments	The complete proteome of Shigella flexneri strain 301 does not contain mdtB. The sequence contains an in-frame codon. The authors have checked the sequence and is believed to be correct.