HAMAP rule MF_01424

General rule information [?]

Accession	MF_01424
Dates	2-FEB-2005 (Created) 19-NOV-2019 (Last updated, Version 23)
Name	MdtC
Scope(s)	Bacteria Enterobacterales
Template(s)	P76399 (MDTC_ECOLI); [ Recover all ]
Triggered by	HAMAP; MF_01424 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier	MDTC
Protein name	RecName: Full=Multidrug resistance protein MdtC; AltName: Full=Multidrug transporter MdtC;
Gene name	Name=mdtC;

Comments [?]

case <OC:Escherichia>
FUNCTION	The MdtABC tripartite complex confers resistance against novobiocin and deoxycholate.
end case
SUBUNIT	Part of a tripartite efflux system composed of MdtA, MdtB and MdtC. MdtC forms a heteromultimer with MdtB.
SUBCELLULAR LOCATION	Cell inner membrane; Multi-pass membrane protein.
case <OC:Escherichia>
INDUCTION	The mdtABC operon is transcriptionally activated by BaeR.
end case
SIMILARITY	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtC subfamily.

Keywords [?]

Gene Ontology [?]

GO:0022857; Molecular function:transmembrane transporter activity

GO:0005886; Cellular component:plasma membrane

Cross-references [?]

Features [?]

Additional information [?]