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Annotation rule MF_01424
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General rule information [?]

Accession MF_01424
Dates 2-FEB-2005 (Created)
19-NOV-2019 (Last updated, Version 23)
Name MdtC
Scope
Bacteria; Enterobacterales
Template P76399 (MDTC_ECOLI)

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
MDTC
Protein name
RecName: Full=Multidrug resistance protein MdtC;
AltName: Full=Multidrug transporter MdtC;
Gene name
mdtC

Comments [?]

case <OC:Escherichia>
Function The MdtABC tripartite complex confers resistance against novobiocin and deoxycholate.
end case
Subunit Part of a tripartite efflux system composed of MdtA, MdtB and MdtC. MdtC forms a heteromultimer with MdtB.
Subcellular location Cell inner membrane; Multi-pass membrane protein.
case <OC:Escherichia>
Induction The mdtABC operon is transcriptionally activated by BaeR.
end case
Similarity Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtC subfamily.

Keywords [?]


Gene Ontology [?]

GO:0022857; Molecular function: transmembrane transporter activity.
GO:0005886; Cellular component: plasma membrane.

Cross-references [?]

Pfam PF00873; ACR_tran; 1;
PRINTS PR00702; ACRIFLAVINRP; 1;

Computed features [?]

General Transmembrane; -; 10-12; trigger=yes;

Additional information [?]

Size range 1021-1036 amino acids
Related rules None
Fusion None