HAMAP rule MF_01434

General rule information [?]

Accession	MF_01434
Dates	15-DEC-2005 (Created) 11-NOV-2020 (Last updated, Version 20)

Name

MGT

Scope

Bacteria; Staphylococcus

Template

Q93Q23 (MGT_STAA8)

Triggered by

HAMAP; MF_01434 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier

MGT

Protein name

RecName:		Full=Monofunctional glycosyltransferase;
		Short=MGT;
		EC 2.4.1.129;
AltName:		Full=Peptidoglycan TGase;

Gene name

mgt

Comments [?]

Function	Peptidoglycan polymerase that catalyzes glycan chain elongation using lipid-linked disaccharide-pentapeptide as the substrate.
Catalytic activity	RHEA:23708: [GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n)-di-trans,octa-cis-undecaprenyl diphosphate + beta-D-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate = [GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n+1)-di-trans-octa-cis-undecaprenyl diphosphate + di-trans,octa-cis-undecaprenyl diphosphate + H(+) EC 2.4.1.129
Pathway	Cell wall biogenesis; peptidoglycan biosynthesis.
Subcellular location	Cell membrane; Single-pass membrane protein.
Similarity	Belongs to the glycosyltransferase 51 family.

Keywords [?]

Cell membrane
Cell shape
Cell wall biogenesis/degradation
Glycosyltransferase
Membrane
Peptidoglycan synthesis
Transferase
Transmembrane
Transmembrane helix

Gene Ontology [?]

GO:0008955; Molecular function: peptidoglycan glycosyltransferase activity.
GO:0009252; Biological process: peptidoglycan biosynthetic process.
GO:0005886; Cellular component: plasma membrane.

Cross-references [?]

Pfam	PF00912; Transgly; 1;

Computed features [?]

General

Transmembrane; -; 1; trigger=yes;

Additional information [?]

Size range	265-280 amino acids
Related rules	None
Fusion	None

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