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Annotation rule MF_01443
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General rule information [?]

Accession MF_01443
Dates 12-JUL-2007 (Created)
19-NOV-2019 (Last updated, Version 12)
Name PrpE
Scope
Bacteria; Bacillaceae
Template O31614 (PRPE_BACSU)
Triggered by

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
PRPE
Protein name
RecName: Full=Bis(5'-nucleosyl)-tetraphosphatase PrpE [asymmetrical];
EC 3.6.1.17;
AltName: Full=Ap4A hydrolase;
AltName: Full=Diadenosine 5',5'''-P1,P4-tetraphosphate asymmetrical hydrolase;
Short=Diadenosine tetraphosphatase;
Gene name
prpE

Comments [?]

Function Asymmetrically hydrolyzes Ap4p to yield AMP and ATP.
Catalytic activity RHEA:22484: H2O + P(1),P(4)-bis(5'-guanosyl) tetraphosphate = GMP + GTP + 2 H(+)
EC 3.6.1.17
Cofactor Ni(2+)
Similarity Belongs to the PrpE family.

Keywords [?]

GTP-binding
Hydrolase
Nickel
Nucleotide-binding

Gene Ontology [?]

GO:0004081; Molecular function: bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity.
GO:0016151; Molecular function: nickel cation binding.

Cross-references [?]

Pfam PF00149; Metallophos; 1;
PRINTS PR00114; STPHPHTASE; 1;

Additional information [?]

Size range 244-250 amino acids
Related rules None
Fusion None


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