HAMAP rule MF_01443

General rule information [?]

Accession	MF_01443
Dates	12-JUL-2007 (Created) 15-FEB-2022 (Last updated, Version 13)

Name

PrpE

Scope

Bacteria; Bacillaceae

Template

O31614 (PRPE_BACSU)

Triggered by

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier

PRPE

Protein name

RecName:		Full=Bis(5'-nucleosyl)-tetraphosphatase PrpE [asymmetrical];
		EC 3.6.1.17;
AltName:		Full=Ap4A hydrolase;
AltName:		Full=Diadenosine 5',5'''-P1,P4-tetraphosphate asymmetrical hydrolase;
		Short=Diadenosine tetraphosphatase;

Gene name

prpE

Comments [?]

Function	Asymmetrically hydrolyzes Ap4p to yield AMP and ATP.
Catalytic activity	RHEA:22484: H2O + P(1),P(4)-bis(5'-guanosyl) tetraphosphate = GMP + GTP + 2 H(+) EC 3.6.1.17
Cofactor	Ni(2+)
Similarity	Belongs to the PrpE family.

Keywords [?]

Gene Ontology [?]

GO:0004081; Molecular function: bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity.
GO:0016151; Molecular function: nickel cation binding.

Cross-references [?]

Pfam	PF00149; Metallophos; 1;
PRINTS	PR00114; STPHPHTASE; 1;

Additional information [?]