HAMAP rule MF_01457

General rule information [?]

Accession	MF_01457
Dates	14-MAY-2010 (Created) 19-NOV-2019 (Last updated, Version 13)

Name

YcgR

Scope

Bacteria; Betaproteobacteria

Bacteria; Gammaproteobacteria

Templates

P76010 (YCGR_ECOLI); Q88EQ6 (YCGR_PSEPK); Q8ZP19 (YCGR_SALTY): [Recover all]

Triggered by

HAMAP; MF_01457 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier

YCGR

Protein name

RecName:		Full=Flagellar brake protein YcgR;
AltName:		Full=Cyclic di-GMP binding protein YcgR;

Gene name

ycgR

Comments [?]

Function	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)-dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility.
Subunit	Monomer. Interacts with the flagellar basal bodies.
Subcellular location	Bacterial flagellum basal body.
Similarity	Belongs to the YcgR family.

Keywords [?]

Bacterial flagellum
c-di-GMP
Nucleotide-binding

Gene Ontology [?]

GO:0035438; Molecular function: cyclic-di-GMP binding.
GO:0071973; Biological process: bacterial-type flagellum-dependent cell motility.
GO:0071945; Biological process: regulation of bacterial-type flagellum-dependent cell motility by regulation of motor speed.

Cross-references [?]

Pfam	PF07238; PilZ; 1; trigger=Yes;
	PF07317; YcgR; 1;

Additional information [?]

Size range	229-287 amino acids
Related rules	None
Fusion	None
Comments	The orthologue in Vibrio cholerae (AC Q9KNC3), although similar, does not have both Pfam domains and so is not considered a member of this family.

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